NEXT GENOME SEQUENCING - AN OVERVIEW

DNA sequencing is the method of determining the nucleotide sequence within a DNA fragment. Next-generation sequencing (NGS) is the catch-all term used to describe different modern sequencing technologies. Such technologies allow sequencing of DNA and RNA much faster and cheaper than commonly used Sanger sequencing. 

NGS allows researchers to perform a wide variety of applications and to study biological systems at a level never before possible with its ultra-high throughput, scalability, and speed.

According to our market analysis, the global next-generation sequencing market size is valued at $4,533 million in 2018. It is estimated to reach $18,565 million by 2026, growing at a CAGR of 19.2% from 2019 to 2026. Based on the stats its evident that, the next generation market is on a rocket trajectory. This article discusses the trends that are responsible for NGS market growth and the top companies that are dominating this market. 

Trends Influencing the Next Generation Market Size

• The need for novel platforms to accommodate advances in bioinformatics and rapid analysis of DNA data paves the way for start-ups, especially for services for next-generation sequencing (NGS). The cost of sequencing has shrunk over the years with the advent of next-generation sequencing. This has a positive impact on this segment's growth.
• The adoption of next generation sequencing-based testing of the is on the increase around the world. This, coupled with attractive policies on healthcare reimbursement, is expected to drive the growth of the segment over the projected period.
• Rising applications in agricultural genomics and oncology research and the need for complex sequencing data analysis give NGS service providers significant opportunities.

Top Companies Dominating the Next Generation Market

1) Illumina

Illumina, Inc. is one of the leading players in academic, clinical, and industrial markets for DNA sequencing and array-based technologies. The company offers products in the life sciences, oncology, reproductive health, forestry, and other emerging markets for applications. The company serves government laboratories, genomic research centers, academic institutions, as well as companies in the pharmaceutical, biotechnology, agri-genomics, commercial molecular diagnostic laboratories, and consumer genomics. Illumina, Inc. has a global presence in Asia-Pacific, North America, Europe, and Latin America

2) Beijing Genomics Institute

The Beijing Genomics Institute (BGI) is the largest genomics organization and non-profit research institution in the world, founded in 1999 and based in Shenzhen, China. The company provides a wide range of next generation commercial sequencing services and genetic testing for medical, agricultural, and environmental applications. Through its subsidiaries, BGI China (Mainland), BGI Asia Pacific, BGI Americas (North and South America), and BGI Europe (Europe and Africa), the company operates throughout the world.

3) QIAGEN N.V.

The organization is committed to providing solutions for Sample to Insight that turn biological samples into molecular insights. QIAGEN provides customers with its workflow in molecular diagnostics, assay technology, bio-services, and automation systems. Genome services of the organization are ideal for custom / tailored projects.

4) Perkinelmer

PerkinElmer, Inc. offers its diagnostics, food, environmental, industrial, life sciences research, and laboratory services markets to its products, services and solutions. The company provides comprehensive solutions for genetic testing that help provide insight into the complex nature of rare and inherited diseases. Some of the company's subsidiaries are amongst many others Caliper Life Sciences, Improvision, Viacell Inc., ViaCord LLC. The business has facilities in Europe (France, Germany, and Belgium), the United States, and Asia (China, India, and Japan).

5) Thermo Fisher Scientific

The company operates through four business segments, namely Analytical Instruments, Life Sciences Solutions, Laboratory Products and Services, and Diagnostic Specialties. The company is providing sequencing solutions for the next generation under the business segment Life Sciences Solution. The business has a strong presence in the United States and China. It sells its products and services in other geographies through a direct sales network, customer-service personnel, online distribution, and third-party distributors.

To conclude, one can say that the challenging genomic research questions of today need a breadth of knowledge beyond the capabilities of conventional DNA sequencing technologies. Next-generation sequencing filled that gap and became a daily method for addressing these issues. This in-turns is causing the NGS market to grow.