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Global PNH and aHUS Market Size, Manufacturers, Supply Chain, Sales Channel and Clients, 2025-2031
Published Date: June 2025
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Report Code: QYRE-Auto-0X9522
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Global PNH and aHUS Market Size Status and Forecast 2022
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Global PNH and aHUS Market Size, Manufacturers, Supply Chain, Sales Channel and Clients, 2025-2031

Code: QYRE-Auto-0X9522
Report
June 2025
Pages:113
QYResearch
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DESCRIPTION
TABLE OF CONTENT
TABLES & FIGURES

PNH and aHUS Market Size

In 2024, the global market size of PNH and aHUS was estimated to be worth US$ 5826 million and is forecast to reach approximately US$ 8940 million by 2031 with a CAGR of 6.4% during the forecast period 2025-2031.

PNH and aHUS Market

PNH and aHUS Market

PNH and aHUS, both are extremely rare and genetic diseases. Due to PNH, destruction of red blood cells of a person occurs quite sooner than it should. It is an acquired hematopoietic stem cell disorder. Hematopoietic stem cells are developed in bone marrow and eventually turn into red blood cells, white blood cells and platelets. A person with PNH has some defected hematopoietic cells which create defective red blood cells. These defective cells are highly susceptible to premature destruction by the complement system. aHUS is a disorders in which blood clots are formed in small blood vessels throughout the body. TMA can lead to heart stroke, attack, kidney failure and death.
United States is the largest consumption place, with a consumption market share nearly 52.1% in 2019. Following United States, Europe is the second largest consumption place with the consumption market share of 26.2%.

Report Scope

This report aims to provide a comprehensive presentation of the global market for PNH and aHUS, with both quantitative and qualitative analysis, to help readers develop business/growth strategies, assess the market competitive situation, analyze their position in the current marketplace, and make informed business decisions regarding PNH and aHUS.
The PNH and aHUS market size, estimations, and forecasts are provided in terms of and revenue ($ millions), considering 2024 as the base year, with history and forecast data for the period from 2020 to 2031. This report segments the global PNH and aHUS market comprehensively. Regional market sizes, concerning products by Type, by Application, and by players, are also provided.
For a more in-depth understanding of the market, the report provides profiles of the competitive landscape, key competitors, and their respective market ranks. The report also discusses technological trends and new product developments.
The report will help the PNH and aHUS companies, new entrants, and industry chain related companies in this market with information on the revenues for the overall market and the sub-segments across the different segments, by company, product type, application, and regions.
Market Segmentation

Scope of PNH and aHUS Market Report

Report Metric Details
Report Name PNH and aHUS Market
Forecasted market size in 2031 approximately US$ 8940 million
CAGR 6.4%
Forecasted years 2025 - 2031
Segment by Type
  • Soliris
  • Ultomiris
Segment by Application
  • PNH
  • aHUS
By Region
  • North America (United States, Canada)
  • Europe (Germany, France, UK, Italy, Russia) Rest of Europe
  • Nordic Countries
  • Asia-Pacific (China, Japan, South Korea)
  • Southeast Asia (India, Australia)
  • Rest of Asia
  • Latin America (Mexico, Brazil)
  • Rest of Latin America
  • Middle East & Africa (Turkey, Saudi Arabia, UAE, Rest of MEA)
By Company Alexion Pharmaceuticals, Alnylam Pharmaceuticals, Omeros Corporation
Forecast units USD million in value
Report coverage Revenue and volume forecast, company share, competitive landscape, growth factors and trends

Chapter Outline

  • Chapter 1: Introduces the report scope of the report, executive summary of different market segments (product type, application, etc), including the market size of each market segment, future development potential, and so on.
  • Chapter 2: Revenue of PNH and aHUS in global and regional level.
  • Chapter 3: Detailed analysis of PNH and aHUS company competitive landscape, revenue, market share and industry ranking, latest development plan, merger, and acquisition information, etc.
  • Chapter 4: Provides profiles of key companies, introducing the basic situation of the main companies in the market in detail, including product descriptions and specifications, PNH and aHUS revenue, gross margin, and recent development, etc.
  • Chapter 5: Provides the analysis of various market segments by Type, covering the revenue, and development potential of each market segment, to help readers find the blue ocean market in different market segments.
  • Chapter 6: Provides the analysis of various market segments by Application, covering the revenue, and development potential of each market segment, to help readers find the blue ocean market in different downstream markets.
  • Chapter 7: North America (US & Canada) by Type, by Application and by country, revenue for each segment.
  • Chapter 8: Europe by Type, by Application and by country, revenue for each segment.
  • Chapter 9: Asia Pacific by Type, by Application and by region, revenue for each segment.
  • Chapter 10: Latin America by Type, by Application and by country, revenue for each segment.
  • Chapter 11: Middle East and Africa, by Type, by Application and by country, revenue for each segment.
  • Chapter 12: Analysis of industrial chain, sales channel, key raw materials, distributors, and customers.
  • Chapter 13: Introduces the market dynamics, latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by manufacturers in the industry, and the analysis of relevant policies in the industry.
  • Chapter 14: Research Findings and Conclusion

FAQ for this report

What is the PNH and aHUS Market size in 2031?

Ans: The PNH and aHUS Market size in 2031 will be approximately US$ 8940 million.

What is the PNH and aHUS Market share by region?

Ans: United States is the largest consumption place, with a consumption market share nearly 52.1% in 2019.

Who are the main players in the PNH and aHUS Market report?

Ans: The main players in the PNH and aHUS Market are Alexion Pharmaceuticals, Alnylam Pharmaceuticals, Omeros Corporation

What are the Application segmentation covered in the PNH and aHUS Market report?

Ans: The Applications covered in the PNH and aHUS Market report are PNH, aHUS

What are the Type segmentation covered in the PNH and aHUS Market report?

Ans: The Types covered in the PNH and aHUS Market report are Soliris, Ultomiris

1 Study Coverage
1.1 PNH and aHUS Product Introduction
1.2 Market by Type
1.2.1 Global PNH and aHUS Market Size Growth Rate by Type (2020 VS 2024 VS 2031)
1.2.2 Soliris
1.2.3 Ultomiris
1.3 Market by Application
1.3.1 Global PNH and aHUS Market Size Growth Rate by Application (2020 VS 2024 VS 2031)
1.3.2 PNH
1.3.3 aHUS
1.4 Assumptions and Limitations
1.5 Study Objectives
1.6 Years Considered
2 Executive Summary
2.1 Global PNH and aHUS Market Size Estimates and Forecasts
2.2 PNH and aHUS Market Size by Region: 2024 Versus 2031
2.2.1 Global PNH and aHUS Revenue by Region: 2020-2025
2.2.2 Global PNH and aHUS Revenue Forecast by Region (2026-2031)
2.2.3 Global PNH and aHUS Revenue Market Share by Region (2020-2031)
3 Market Segments
3.1 Breakdown Data by Type
3.1.1 Global PNH and aHUS Revenue by Type (2020-2031)
3.1.2 Global PNH and aHUS Revenue Market Share by Type (2020-2031)
3.2 Breakdown Data by Application
3.2.1 Global PNH and aHUS Revenue by Application (2020-2031)
3.2.2 Global PNH and aHUS Revenue Market Share by Application (2020-2031)
3.3 by Type and by Application Crossing Analysis
3.3.1 Soliris of PNH and aHUS Revenue Market Share by Application
3.3.2 Ultomiris of PNH and aHUS Revenue Market Share by Application
4 Global PNH and aHUS by Company
4.1 Global PNH and aHUS Revenue by Company (2020-2025)
4.2 Global PNH and aHUS Revenue Share by Company (2020-2025)
4.3 Competitive Landscape
4.3.1 Key PNH and aHUS Companies around the World: Ranking by Revenue
4.3.2 Global PNH and aHUS Market Concentration Ratio (CR5 and HHI) & (2020-2025)
4.3.3 Global PNH and aHUS Market Share by Company Type (Tier 1, Tier 2, and Tier 3)
4.4 Global PNH and aHUS Companies Headquarters & Product Type
4.4.1 Global PNH and aHUS Companies Headquarters
4.4.2 Date of International Companies Enter into PNH and aHUS Market
4.4.3 Global PNH and aHUS Companies Product & Service
4.4.4 Soliris Revenue Market Share of PNH and aHUS by Company
4.4.5 Ultomiris Revenue Market Share of PNH and aHUS by Company
4.5 Global PNH and aHUS Mergers & Acquisitions, Expansion Plans
5 Company Profiles
5.1 Alexion Pharmaceuticals
5.1.1 Alexion Pharmaceuticals Corporation Information
5.1.2 Alexion Pharmaceuticals Description, Business Overview
5.1.3 Alexion Pharmaceuticals PNH and aHUS Products Offered
5.1.4 Alexion Pharmaceuticals PNH and aHUS Revenue and Gross Margin (2020-2025)
5.1.5 Alexion Pharmaceuticals PNH and aHUS Revenue by Product in 2024
5.1.6 Alexion Pharmaceuticals PNH and aHUS Revenue by Application in 2024
5.1.7 Alexion Pharmaceuticals PNH and aHUS Revenue by Geographic Area in 2024
5.1.8 Alexion Pharmaceuticals Recent Developments
5.2 Alnylam Pharmaceuticals
5.2.1 Alnylam Pharmaceuticals Corporation Information
5.2.2 Alnylam Pharmaceuticals Description, Business Overview
5.2.3 Alnylam Pharmaceuticals PNH and aHUS Products Offered
5.2.4 Alnylam Pharmaceuticals PNH and aHUS Revenue and Gross Margin (2020-2025)
5.2.5 Alnylam Pharmaceuticals PNH and aHUS Revenue by Product in 2024
5.2.6 Alnylam Pharmaceuticals PNH and aHUS Revenue by Application in 2024
5.2.7 Alnylam Pharmaceuticals PNH and aHUS Revenue by Geographic Area in 2024
5.2.8 Alnylam Pharmaceuticals Recent Developments
5.3 Omeros Corporation
5.3.1 Omeros Corporation Corporation Information
5.3.2 Omeros Corporation Description, Business Overview
5.3.3 Omeros Corporation PNH and aHUS Products Offered
5.3.4 Omeros Corporation PNH and aHUS Revenue and Gross Margin (2020-2025)
5.3.5 Omeros Corporation PNH and aHUS Revenue by Product in 2024
5.3.6 Omeros Corporation PNH and aHUS Revenue by Application in 2024
5.3.7 Omeros Corporation PNH and aHUS Revenue by Geographic Area in 2024
5.3.8 Omeros Corporation Recent Developments
6 North America
6.1 North America PNH and aHUS Market Size YoY Growth 2020-2031
6.2 North America PNH and aHUS Market Facts & Figures by Country (2020-2031)
6.3 North America PNH and aHUS Revenue by Type (2020-2025)
6.4 North America PNH and aHUS Revenue by Application (2020-2025)
7 Asia-Pacific
7.1 Asia-Pacific PNH and aHUS Market Size YoY Growth 2020-2031
7.2 Asia-Pacific PNH and aHUS Market Facts & Figures by Region (2020-2031)
7.3 Asia-Pacific PNH and aHUS Revenue by Type (2020-2025)
7.4 Asia-Pacific PNH and aHUS Revenue by Application (2020-2025)
8 Europe
8.1 Europe PNH and aHUS Market Size YoY Growth 2020-2031
8.2 Europe PNH and aHUS Market Facts & Figures by Country (2020-2031)
8.3 Europe PNH and aHUS Revenue by Type (2020-2025)
8.4 Europe PNH and aHUS Revenue by Application (2020-2025)
9 Latin America
9.1 Latin America PNH and aHUS Market Size YoY Growth 2020-2031
9.2 Latin America PNH and aHUS Market Facts & Figures by Country (2020-2031)
9.3 Latin America PNH and aHUS Revenue by Type (2020-2025)
9.4 Latin America PNH and aHUS Revenue by Application (2020-2025)
10 Middle East and Africa
10.1 Latin America PNH and aHUS Market Size YoY Growth 2020-2031
10.2 Middle East and Africa PNH and aHUS Market Facts & Figures by Country (2020-2031)
10.3 Middle East and Africa PNH and aHUS Revenue by Type (2020-2025)
10.4 Middle East and Africa PNH and aHUS Revenue by Application (2020-2025)
11 Supply Chain and Sales Channel analysis
11.1 PNH and aHUS Supply Chain Analysis
11.2 PNH and aHUS Key Raw Materials and Upstream Suppliers
11.3 PNH and aHUS Clients Analysis
11.4 PNH and aHUS Sales Channel and Sales Model Analysis
11.4.1 PNH and aHUS Distribution Channel Analysis: Indirect Sales VS Direct Sales
11.4.2 PNH and aHUS Distribution Channel Analysis: Online Sales VS Offline Sales
11.4.3 PNH and aHUS Distributors
12 PNH and aHUS Market Dynamics
12.1 PNH and aHUS Industry Trends
12.2 PNH and aHUS Market Drivers
12.3 PNH and aHUS Market Challenges
12.4 PNH and aHUS Market Restraints
13 Research Findings and Conclusion
14 Appendix
14.1 Research Methodology
14.1.1 Methodology/Research Approach
14.1.1.1 Research Programs/Design
14.1.1.2 Market Size Estimation
14.1.1.3 Market Breakdown and Data Triangulation
14.1.2 Data Source
14.1.2.1 Secondary Sources
14.1.2.2 Primary Sources
14.2 Author Details
14.3 Disclaimer
List of Tables
 Table 1. Global PNH and aHUS Market Size Growth Rate (CAGR) by Type (US$ Million): 2020 VS 2024 VS 2031
 Table 2. Global PNH and aHUS Market Size Growth by Application (US$ Million): 2020 VS 2024 VS 2031
 Table 3. Global PNH and aHUS Market Size by Region (US$ Million): 2024 VS 2031
 Table 4. Global PNH and aHUS Revenue by Region (2020-2025) & (US$ Million)
 Table 5. Global PNH and aHUS Revenue Forecast by Region (2026-2031) & (US$ Million)
 Table 6. Global PNH and aHUS Revenue by Type (2020-2025) & (US$ Million)
 Table 7. Global PNH and aHUS Revenue Forecast by Type (2026-2031) & (US$ Million)
 Table 8. Global PNH and aHUS Revenue by Application (2020-2025) & (US$ Million)
 Table 9. Global PNH and aHUS Revenue Forecast by Application (2026-2031) & (US$ Million)
 Table 10. PNH and aHUS Revenue by Company (2020-2025) & (US$ Million)
 Table 11. PNH and aHUS Revenue Share by Company (2020-2025)
 Table 12. Ranking of Global Top PNH and aHUS Players by Revenue (US$ Million) in 2024
 Table 13. Global PNH and aHUS Companies Market Concentration Ratio (CR5 and HHI) & (2020-2025)
 Table 14. Global PNH and aHUS by Company Type (Tier 1, Tier 2, and Tier 3) & (based on the Revenue in PNH and aHUS as of 2024)
 Table 15. Global PNH and aHUS Companies Headquarters
 Table 16. Date of International Companies Enter into PNH and aHUS Market
 Table 17. Global PNH and aHUS Companies Product & Service
 Table 18. Global PNH and aHUS Mergers & Acquisitions, Expansion Plans
 Table 19. Alexion Pharmaceuticals Corporation Information
 Table 20. Alexion Pharmaceuticals Description and Business Overview
 Table 21. Alexion Pharmaceuticals PNH and aHUS Product
 Table 22. Alexion Pharmaceuticals PNH and aHUS Revenue (US$ Million) and Gross Margin (2020-2025)
 Table 23. Alexion Pharmaceuticals Revenue Proportion of PNH and aHUS by Product in 2024
 Table 24. Alexion Pharmaceuticals Revenue Proportion of PNH and aHUS by Application in 2024
 Table 25. Alexion Pharmaceuticals Revenue Proportion of PNH and aHUS by Geographic Area in 2024
 Table 26. Alexion Pharmaceuticals Recent Developments
 Table 27. Alnylam Pharmaceuticals Corporation Information
 Table 28. Alnylam Pharmaceuticals Description and Business Overview
 Table 29. Alnylam Pharmaceuticals PNH and aHUS Product
 Table 30. Alnylam Pharmaceuticals PNH and aHUS Revenue (US$ Million) and Gross Margin (2020-2025)
 Table 31. Alnylam Pharmaceuticals Revenue Proportion of PNH and aHUS by Product in 2024
 Table 32. Alnylam Pharmaceuticals Revenue Proportion of PNH and aHUS by Application in 2024
 Table 33. Alnylam Pharmaceuticals Revenue Proportion of PNH and aHUS by Geographic Area in 2024
 Table 34. Alnylam Pharmaceuticals Recent Developments
 Table 35. Omeros Corporation Corporation Information
 Table 36. Omeros Corporation Description and Business Overview
 Table 37. Omeros Corporation PNH and aHUS Product
 Table 38. Omeros Corporation PNH and aHUS Revenue (US$ Million) and Gross Margin (2020-2025)
 Table 39. Omeros Corporation Revenue Proportion of PNH and aHUS by Product in 2024
 Table 40. Omeros Corporation Revenue Proportion of PNH and aHUS by Application in 2024
 Table 41. Omeros Corporation Revenue Proportion of PNH and aHUS by Geographic Area in 2024
 Table 42. Omeros Corporation Recent Developments
 Table 43. North America PNH and aHUS Revenue by Country (2020-2025) & (US$ Million)
 Table 44. North America PNH and aHUS Revenue by Country (2026-2031) & (US$ Million)
 Table 45. North America PNH and aHUS Revenue by Type (2020-2025) & (US$ Million)
 Table 46. North America PNH and aHUS Revenue by Application (2020-2025) & (US$ Million)
 Table 47. Asia-Pacific PNH and aHUS Revenue by Region (2020-2025) & (US$ Million)
 Table 48. Asia-Pacific PNH and aHUS Revenue by Region (2026-2031) & (US$ Million)
 Table 49. Asia-Pacific PNH and aHUS Revenue by Type (2020-2025) & (US$ Million)
 Table 50. Asia-Pacific PNH and aHUS Revenue by Application (2020-2025) & (US$ Million)
 Table 51. Europe PNH and aHUS Revenue by Country (2020-2025) & (US$ Million)
 Table 52. Europe PNH and aHUS Revenue by Country (2026-2031) & (US$ Million)
 Table 53. Europe PNH and aHUS Revenue by Type (2020-2025) & (US$ Million)
 Table 54. Europe PNH and aHUS Revenue by Application (2020-2025) & (US$ Million)
 Table 55. Latin America PNH and aHUS Revenue by Country (2020-2025) & (US$ Million)
 Table 56. Latin America PNH and aHUS Revenue by Country (2026-2031) & (US$ Million)
 Table 57. Latin America PNH and aHUS Revenue by Type (2020-2025) & (US$ Million)
 Table 58. Latin America PNH and aHUS Revenue by Application (2020-2025) & (US$ Million)
 Table 59. Middle East and Africa PNH and aHUS Revenue by Country (2020-2025) & (US$ Million)
 Table 60. Middle East and Africa PNH and aHUS Revenue by Country (2026-2031) & (US$ Million)
 Table 61. Middle East and Africa PNH and aHUS Revenue by Type (2020-2025) & (US$ Million)
 Table 62. Middle East and Africa PNH and aHUS Revenue by Application (2020-2025) & (US$ Million)
 Table 63. PNH and aHUS Key Raw Materials, Industry Status and Trend
 Table 64. PNH and aHUS Key Raw Materials and Upstream Suppliers
 Table 65. PNH and aHUS Clients Status and Trend
 Table 66. PNH and aHUS Typical Clients
 Table 67. PNH and aHUS Distributors
 Table 68. PNH and aHUS Market Trends
 Table 69. PNH and aHUS Market Drivers
 Table 70. PNH and aHUS Market Challenges
 Table 71. PNH and aHUS Market Restraints
 Table 72. Research Programs/Design for This Report
 Table 73. Key Data Information from Secondary Sources
 Table 74. Key Data Information from Primary Sources


List of Figures
 Figure 1. PNH and aHUS Product Picture
 Figure 2. Global PNH and aHUS Market Size by Type (US$ Million): 2020 VS 2024 VS 2031
 Figure 3. Global PNH and aHUS Revenue Market Share by Type in 2024 & 2031
 Figure 4. Soliris Product Picture
 Figure 5. Ultomiris Product Picture
 Figure 6. Global PNH and aHUS Market Size by Application (US$ Million): 2020 VS 2024 VS 2031
 Figure 7. Global PNH and aHUS Revenue Market Share by Application in 2024 & 2031
 Figure 8. PNH
 Figure 9. aHUS
 Figure 10. PNH and aHUS Report Years Considered
 Figure 11. Global PNH and aHUS Revenue, (US$ Million), 2020 VS 2024 VS 2031
 Figure 12. Global PNH and aHUS Market Size (2020-2031) & (US$ Million)
 Figure 13. Global PNH and aHUS Market Size Market Share by Region: 2024 Versus 2031
 Figure 14. Global PNH and aHUS Revenue Market Share by Region (2020-2031)
 Figure 15. Global PNH and aHUS Revenue Market Share Forecast by Type (2020-2031)
 Figure 16. Global PNH and aHUS Revenue Market Share Forecast by Application (2020-2031)
 Figure 17. Soliris of PNH and aHUS Revenue Market Share by Application, 2024 VS 2031
 Figure 18. Ultomiris of PNH and aHUS Revenue Market Share by Application, 2024 VS 2031
 Figure 19. PNH and aHUS Revenue Share by Company (2024)
 Figure 20. PNH and aHUS Market Share by Company Type (Tier 1, Tier 2, and Tier 3): 2020 VS 2024
 Figure 21. Soliris Revenue Proportion by Company in 2024
 Figure 22. Ultomiris Revenue Proportion by Company in 2024
 Figure 23. North America PNH and aHUS Revenue 2020-2031 (US$ Million)
 Figure 24. North America PNH and aHUS Revenue Market Share by Type (2020-2025)
 Figure 25. North America PNH and aHUS Revenue Market Share by Application (2020-2025)
 Figure 26. Asia-Pacific PNH and aHUS Revenue 2020-2031 (US$ Million)
 Figure 27. Asia-Pacific PNH and aHUS Revenue Market Share by Region (2020-2031)
 Figure 28. Asia-Pacific PNH and aHUS Revenue Market Share by Type (2020-2025)
 Figure 29. Asia-Pacific PNH and aHUS Revenue Market Share by Application (2020-2025)
 Figure 30. Europe PNH and aHUS Revenue Growth Rate 2020-2031 (US$ Million)
 Figure 31. Europe PNH and aHUS Revenue Market Share by Country (2020-2031)
 Figure 32. Europe PNH and aHUS Revenue Market Share by Type (2020-2025)
 Figure 33. Europe PNH and aHUS Revenue Market Share by Application (2020-2025)
 Figure 34. Latin America PNH and aHUS Revenue Growth Rate 2020-2031 (US$ Million)
 Figure 35. Latin America PNH and aHUS Revenue Market Share by Country (2020-2031)
 Figure 36. Latin America PNH and aHUS Revenue Market Share by Type (2020-2025)
 Figure 37. Latin America PNH and aHUS Revenue Market Share by Application (2020-2025)
 Figure 38. Middle East and Africa PNH and aHUS Revenue Growth Rate 2020-2031 (US$ Million)
 Figure 39. Middle East and Africa PNH and aHUS Revenue Market Share by Country (2020-2031)
 Figure 40. Middle East and Africa PNH and aHUS Revenue Market Share by Type (2020-2025)
 Figure 41. Middle East and Africa PNH and aHUS Revenue Market Share by Application (2020-2025)
 Figure 42. PNH and aHUS Supply Chain (Upstream and Downstream Market)
 Figure 43. Global Production Market Share of PNH and aHUS Raw Materials by Region in 2024
 Figure 44. PNH and aHUS Distribution Channels
 Figure 45. Global PNH and aHUS Percentage 2020-2031: Indirect Sales VS Direct Sales
 Figure 46. Global PNH and aHUS Percentage 2020-2031: Online Sales VS Offline Sales
 Figure 47. Bottom-up and Top-down Approaches for This Report
 Figure 48. Data Triangulation
 Figure 49. Key Executives Interviewed
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