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Global Nucleic Acid-based Therapy Market Outlook, In‑Depth Analysis & Forecast to 2031
Published Date: October 2025
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Report Code: QYRE-Auto-30A16983
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Global Nucleic Acid based Therapy Market Research Report 2024
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Global Nucleic Acid-based Therapy Market Outlook, In‑Depth Analysis & Forecast to 2031

Code: QYRE-Auto-30A16983
Report
October 2025
Pages:149
QYResearch
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DESCRIPTION
TABLE OF CONTENT
TABLES & FIGURES

Nucleic Acid-based Therapy Market Size

The global Nucleic Acid-based Therapy market is projected to grow from US$ 12950 million in 2024 to US$ 16660 million by 2031, at a CAGR of 3.7% (2025-2031), driven by critical product segments and diverse end‑use applications.

Nucleic Acid-based Therapy Market

Nucleic Acid-based Therapy Market

Nucleic acid drugs, also known as nucleic acid-based therapeutics, are a class of pharmaceuticals designed to treat various diseases by targeting specific genes or genetic processes within the human body. They are distinct fromtraditional small molecule drugs and instead rely on nucleic acids, which are the building blocks of genetic information. Nucleic acid drugs encompass various types of pharmaceuticals that use nucleic acids, such as DNA or RNA, as their active components to target specific genes or genetic processes.
From a downstream perspective, Neuromuscular Diseases accounted for % of 2024 revenue, surging to US$ million by 2031 (CAGR: % from 2025–2031).
Nucleic Acid-based Therapy leading manufacturers including Sarepta Therapeutics, Ionis Pharmaceuticals, Alnylam, Biogen, Nippon Shinyaku, Sobi, Novartis, BioNTech, Pfizer, Moderna Therapeutics, etc., dominate supply; the top five capture approximately % of global revenue, with Sarepta Therapeutics leading 2024 sales at US$ million.
Regional Outlook:
North America rose from US$ million in 2024 to a forecast US$ million by 2031 (CAGR %).
Asia‑Pacific will expand from US$ million to US$ million (CAGR  %), led by China (US$ million in 2024, % share rising to % by 2031), Japan (CAGR %), South Korea (CAGR %), and Southeast Asia (CAGR %).
Europe is set to grow from US$ million to US$ million (CAGR %), with Germany projected to hit US$ million by 2031 (CAGR %).

Report Includes:

This definitive report equips CEOs, marketing directors, and investors with a 360° view of the global Nucleic Acid-based Therapy market across value chain. It analyzes historical revenue data (2020–2024) and delivers forecasts through 2031, illuminating demand trends and growth drivers.
By segmenting the market by Type and by Application, the study quantifies market size, growth rates, niche opportunities, and substitution risks, and analyzes downstream customers distribution pattern.
Granular regional insights cover five major markets—North America, Europe, APAC, South America, and MEA—with in‑depth analysis of 20+ countries, detailing dominant products, competitive landscape, and downstream demand trends.
Critical competitive intelligence profiles players—revenue, margins, pricing strategies, and major customers—and dissects the top-player positioning across product lines, applications, and regions to reveal strategic strengths.
A concise Industry‑chain overview maps upstream, middlestream, and downstream distribution dynamics to identify strategic gaps and unmet demand.
Market Segmentation

Scope of Nucleic Acid-based Therapy Market Report

Report Metric Details
Report Name Nucleic Acid-based Therapy Market
Accounted market size in 2024 US$ 12950 million
Forecasted market size in 2031 US$ 16660 million
CAGR 3.7%
Base Year 2024
Forecasted years 2025 - 2031
Segment by Type
  • Antisense Oligonucleotides (ASO)
  • siRNA
  • mRNA
Segment by Application
  • Neuromuscular Diseases
  • hATTR
  • COVID-19
  • Other
Sales by Region
  • North America (United States, Canada)
  • Europe (Germany, France, UK, Italy, Russia) Rest of Europe
  • Nordic Countries
  • Asia-Pacific (China, Japan, South Korea)
  • Southeast Asia (India, Australia)
  • Rest of Asia
  • Latin America (Mexico, Brazil)
  • Rest of Latin America
  • Middle East & Africa (Turkey, Saudi Arabia, UAE, Rest of MEA)
By Company Sarepta Therapeutics, Ionis Pharmaceuticals, Alnylam, Biogen, Nippon Shinyaku, Sobi, Novartis, BioNTech, Pfizer, Moderna Therapeutics, Jazz Pharmaceuticals, CureVac, Regulus Therapeutics, ProQR, Secarna, MiNA Therapeutics, Sylentis, Arrowhead, Silence Therapeutics, Dicerna
Forecast units USD million in value
Report coverage Revenue and volume forecast, company share, competitive landscape, growth factors and trends

Chapter Outline

  • Chapter 1: Defines the Nucleic Acid-based Therapy study scope, segments the market by Type and by Application, etc, highlights segment size and growth potential.
  • Chapter 2: Offers current market state, projects global revenue and sales to 2031, pinpointing high consumption regions and emerging market catalysts
  • Chapter 3: Dissects the player landscape—ranks by revenue and profitability, details Player performance by product type and evaluates concentration alongside M&A moves.
  • Chapter 4: Unlocks high margin product segments—compares revenue, ASP, and technology differentiators, highlighting growth niches and substitution risks
  • Chapter 5: Targets downstream market opportunities—evaluates market size by Application, identifies emerging use cases, and profiles leading customers by region and by Application.
  • Chapter 6: North America—breaks down market size by Type, by Application and country, profiles key players and assesses growth drivers and barriers.
  • Chapter 7: Europe—analyses regional market by Type, by Application and players, flagging drivers and barriers.
  • Chapter 8: Asia Pacific—quantifies market size by Type, by Application, and region/country, profiles top players, and uncovers high potential expansion areas.
  • Chapter 9: Central & South America—measures market size by Type, by Application, and country, profiles top players, and identifies investment opportunities and challenges.
  • Chapter 10: Middle East and Africa—evaluates market size by Type, by Application, and country, profiles key players, and outlines investment prospects and market hurdles
  • Chapter 11: Profiles players in depth—details product specs, revenue, margins; Top-tier players 2024 sales breakdowns by Product type, by Application, by region SWOT analysis, and recent strategic developments.
  • Chapter 12: Industry chain—analyses upstream, cost drivers, plus downstream channels.
  • Chapter 13: Market dynamics—explores drivers, restraints, regulatory impacts, and risk mitigation strategies.
  • Chapter 14: Actionable conclusions and strategic recommendations.
  • Why This Report:
  • Beyond standard market data, this analysis provides a clear profitability roadmap—empowering you to:
  • Allocate capital strategically to high growth regions (Chapters 6–10) and margin rich segments (Chapter 5).
  • Negotiate from strength with suppliers (Chapter 12) and customers (Chapter 5) using cost and demand intelligence.
  • Outmaneuver competitors with granular insights into their operations, margins, and strategies (Chapters 3 and 11).
  • Capitalize on the projected billion‑dollar opportunity with data‑driven regional and segment tactics (Chapter 12-14).
  • Leverage this 360° intelligence to turn market complexity into actionable competitive advantage.

FAQ for this report

How fast is Nucleic Acid-based Therapy Market growing?

Ans: The Nucleic Acid-based Therapy Market witnessing a CAGR of 3.7% during the forecast period 2025-2031.

What is the Nucleic Acid-based Therapy Market size in 2031?

Ans: The Nucleic Acid-based Therapy Market size in 2031 will be US$ 16660 million.

Who are the main players in the Nucleic Acid-based Therapy Market report?

Ans: The main players in the Nucleic Acid-based Therapy Market are Sarepta Therapeutics, Ionis Pharmaceuticals, Alnylam, Biogen, Nippon Shinyaku, Sobi, Novartis, BioNTech, Pfizer, Moderna Therapeutics, Jazz Pharmaceuticals, CureVac, Regulus Therapeutics, ProQR, Secarna, MiNA Therapeutics, Sylentis, Arrowhead, Silence Therapeutics, Dicerna

What are the Application segmentation covered in the Nucleic Acid-based Therapy Market report?

Ans: The Applications covered in the Nucleic Acid-based Therapy Market report are Neuromuscular Diseases, hATTR, COVID-19, Other

What are the Type segmentation covered in the Nucleic Acid-based Therapy Market report?

Ans: The Types covered in the Nucleic Acid-based Therapy Market report are Antisense Oligonucleotides (ASO), siRNA, mRNA

1 Study Coverage
1.1 Introduction to Nucleic Acid-based Therapy: Definition, Properties, and Key Attributes
1.2 Market Segmentation by Type
1.2.1 Global Nucleic Acid-based Therapy Market Size by Type, 2020 VS 2024 VS 2031
1.2.2 Antisense Oligonucleotides (ASO)
1.2.3 siRNA
1.2.4 mRNA
1.3 Market Segmentation by Application
1.3.1 Global Nucleic Acid-based Therapy Market Size by Application, 2020 VS 2024 VS 2031
1.3.2 Neuromuscular Diseases
1.3.3 hATTR
1.3.4 COVID-19
1.3.5 Other
1.4 Assumptions and Limitations
1.5 Study Objectives
1.6 Years Considered
2 Executive Summary
2.1 Global Nucleic Acid-based Therapy Revenue Estimates and Forecasts 2020-2031
2.2 Global Nucleic Acid-based Therapy Revenue by Region
2.2.1 Revenue Comparison: 2020 VS 2024 VS 2031
2.2.2 Historical and Forecasted Revenue by Region (2020-2031)
2.2.3 Global Revenue Market Share by Region (2020-2031)
2.2.4 Emerging Market Focus: Growth Drivers & Investment Trends
3 Competition by Players
3.1 Global Nucleic Acid-based Therapy Player Revenue Rankings and Profitability
3.1.1 Global Revenue (Value) by Players (2020-2025)
3.1.2 Global Key Player Revenue Ranking (2023 vs. 2024)
3.1.3 Revenue-Based Tier Segmentation (Tier 1, Tier 2, and Tier 3)
3.1.4 Gross Margin by Top Player (2020 VS 2024)
3.2 Global Nucleic Acid-based Therapy Companies Headquarters and Service Footprint
3.3 Main Product Type Market Size by Players
3.3.1 Antisense Oligonucleotides (ASO) Market Size by Players
3.3.2 siRNA Market Size by Players
3.3.3 mRNA Market Size by Players
3.4 Global Nucleic Acid-based Therapy Market Concentration and Dynamics
3.4.1 Global Market Concentration (CR5 and HHI)
3.4.2 Entrant/Exit Impact Analysis
3.4.3 Strategic Moves: M&A, Expansion, R&D Investment
4 Global Product Segmentation Analysis
4.1 Global Nucleic Acid-based Therapy Revenue Trends by Type
4.1.1 Global Historical and Forecasted Revenue by Type (2020-2031)
4.1.2 Global Revenue Market Share by Type (2020-2031)
4.2 Key Product Attributes and Differentiation
4.3 Subtype Dynamics: Growth Leaders, Profitability and Risk
4.3.1 High-Growth Niches and Adoption Drivers
4.3.2 Profitability Hotspots and Cost Drivers
4.3.3 Substitution Threats
5 Global Downstream Application Analysis
5.1 Global Nucleic Acid-based Therapy Revenue by Application
5.1.1 Global Historical and Forecasted Revenue by Application (2020-2031)
5.1.2 Revenue Market Share by Application (2020-2031)
5.1.3 High-Growth Application Identification
5.1.4 Emerging Application Case Studies
5.2 Downstream Customer Analysis
5.2.1 Top Customers by Region
5.2.2 Top Customers by Application
6 North America
6.1 North America Market Size (2020-2031)
6.2 North America Key Players Revenue in 2024
6.3 North America Nucleic Acid-based Therapy Market Size by Type (2020-2031)
6.4 North America Nucleic Acid-based Therapy Market Size by Application (2020-2031)
6.5 North America Growth Accelerators and Market Barriers
6.6 North America Nucleic Acid-based Therapy Market Size by Country
6.6.1 North America Revenue Trends by Country
6.6.2 US
6.6.3 Canada
6.6.4 Mexico
7 Europe
7.1 Europe Market Size (2020-2031)
7.2 Europe Key Players Revenue in 2024
7.3 Europe Nucleic Acid-based Therapy Market Size by Type (2020-2031)
7.4 Europe Nucleic Acid-based Therapy Market Size by Application (2020-2031)
7.5 Europe Growth Accelerators and Market Barriers
7.6 Europe Nucleic Acid-based Therapy Market Size by Country
7.6.1 Europe Revenue Trends by Country
7.6.2 Germany
7.6.3 France
7.6.4 U.K.
7.6.5 Italy
7.6.6 Russia
8 Asia-Pacific
8.1 Asia-Pacific Market Size (2020-2031)
8.2 Asia-Pacific Key Players Revenue in 2024
8.3 Asia-Pacific Nucleic Acid-based Therapy Market Size by Type (2020-2031)
8.4 Asia-Pacific Nucleic Acid-based Therapy Market Size by Application (2020-2031)
8.5 Asia-Pacific Growth Accelerators and Market Barriers
8.6 Asia-Pacific Nucleic Acid-based Therapy Market Size by Region
8.6.1 Asia-Pacific Revenue Trends by Region
8.7 China
8.8 Japan
8.9 South Korea
8.10 Australia
8.11 India
8.12 Southeast Asia
8.12.1 Indonesia
8.12.2 Vietnam
8.12.3 Malaysia
8.12.4 Philippines
8.12.5 Singapore
9 Central and South America
9.1 Central and South America Market Size (2020-2031)
9.2 Central and South America Key Players Revenue in 2024
9.3 Central and South America Nucleic Acid-based Therapy Market Size by Type (2020-2031)
9.4 Central and South America Nucleic Acid-based Therapy Market Size by Application (2020-2031)
9.5 Central and South America Investment Opportunities and Key Challenges
9.6 Central and South America Nucleic Acid-based Therapy Market Size by Country
9.6.1 Central and South America Revenue Trends by Country (2020 VS 2024 VS 2031)
9.6.2 Brazil
9.6.3 Argentina
10 Middle East and Africa
10.1 Middle East and Africa Market Size (2020-2031)
10.2 Middle East and Africa Key Players Revenue in 2024
10.3 Middle East and Africa Nucleic Acid-based Therapy Market Size by Type (2020-2031)
10.4 Middle East and Africa Nucleic Acid-based Therapy Market Size by Application (2020-2031)
10.5 Middle East and Africa Investment Opportunities and Key Challenges
10.6 Middle East and Africa Nucleic Acid-based Therapy Market Size by Country
10.6.1 Middle East and Africa Revenue Trends by Country (2020 VS 2024 VS 2031)
10.6.2 GCC Countries
10.6.3 Israel
10.6.4 Egypt
10.6.5 South Africa
11 Corporate Profile
11.1 Sarepta Therapeutics
11.1.1 Sarepta Therapeutics Corporation Information
11.1.2 Sarepta Therapeutics Business Overview
11.1.3 Sarepta Therapeutics Nucleic Acid-based Therapy Product Features and Attributes
11.1.4 Sarepta Therapeutics Nucleic Acid-based Therapy Revenue and Gross Margin (2020-2025)
11.1.5 Sarepta Therapeutics Nucleic Acid-based Therapy Revenue by Product in 2024
11.1.6 Sarepta Therapeutics Nucleic Acid-based Therapy Revenue by Application in 2024
11.1.7 Sarepta Therapeutics Nucleic Acid-based Therapy Revenue by Geographic Area in 2024
11.1.8 Sarepta Therapeutics Nucleic Acid-based Therapy SWOT Analysis
11.1.9 Sarepta Therapeutics Recent Developments
11.2 Ionis Pharmaceuticals
11.2.1 Ionis Pharmaceuticals Corporation Information
11.2.2 Ionis Pharmaceuticals Business Overview
11.2.3 Ionis Pharmaceuticals Nucleic Acid-based Therapy Product Features and Attributes
11.2.4 Ionis Pharmaceuticals Nucleic Acid-based Therapy Revenue and Gross Margin (2020-2025)
11.2.5 Ionis Pharmaceuticals Nucleic Acid-based Therapy Revenue by Product in 2024
11.2.6 Ionis Pharmaceuticals Nucleic Acid-based Therapy Revenue by Application in 2024
11.2.7 Ionis Pharmaceuticals Nucleic Acid-based Therapy Revenue by Geographic Area in 2024
11.2.8 Ionis Pharmaceuticals Nucleic Acid-based Therapy SWOT Analysis
11.2.9 Ionis Pharmaceuticals Recent Developments
11.3 Alnylam
11.3.1 Alnylam Corporation Information
11.3.2 Alnylam Business Overview
11.3.3 Alnylam Nucleic Acid-based Therapy Product Features and Attributes
11.3.4 Alnylam Nucleic Acid-based Therapy Revenue and Gross Margin (2020-2025)
11.3.5 Alnylam Nucleic Acid-based Therapy Revenue by Product in 2024
11.3.6 Alnylam Nucleic Acid-based Therapy Revenue by Application in 2024
11.3.7 Alnylam Nucleic Acid-based Therapy Revenue by Geographic Area in 2024
11.3.8 Alnylam Nucleic Acid-based Therapy SWOT Analysis
11.3.9 Alnylam Recent Developments
11.4 Biogen
11.4.1 Biogen Corporation Information
11.4.2 Biogen Business Overview
11.4.3 Biogen Nucleic Acid-based Therapy Product Features and Attributes
11.4.4 Biogen Nucleic Acid-based Therapy Revenue and Gross Margin (2020-2025)
11.4.5 Biogen Nucleic Acid-based Therapy Revenue by Product in 2024
11.4.6 Biogen Nucleic Acid-based Therapy Revenue by Application in 2024
11.4.7 Biogen Nucleic Acid-based Therapy Revenue by Geographic Area in 2024
11.4.8 Biogen Nucleic Acid-based Therapy SWOT Analysis
11.4.9 Biogen Recent Developments
11.5 Nippon Shinyaku
11.5.1 Nippon Shinyaku Corporation Information
11.5.2 Nippon Shinyaku Business Overview
11.5.3 Nippon Shinyaku Nucleic Acid-based Therapy Product Features and Attributes
11.5.4 Nippon Shinyaku Nucleic Acid-based Therapy Revenue and Gross Margin (2020-2025)
11.5.5 Nippon Shinyaku Nucleic Acid-based Therapy Revenue by Product in 2024
11.5.6 Nippon Shinyaku Nucleic Acid-based Therapy Revenue by Application in 2024
11.5.7 Nippon Shinyaku Nucleic Acid-based Therapy Revenue by Geographic Area in 2024
11.5.8 Nippon Shinyaku Nucleic Acid-based Therapy SWOT Analysis
11.5.9 Nippon Shinyaku Recent Developments
11.6 Sobi
11.6.1 Sobi Corporation Information
11.6.2 Sobi Business Overview
11.6.3 Sobi Nucleic Acid-based Therapy Product Features and Attributes
11.6.4 Sobi Nucleic Acid-based Therapy Revenue and Gross Margin (2020-2025)
11.6.5 Sobi Recent Developments
11.7 Novartis
11.7.1 Novartis Corporation Information
11.7.2 Novartis Business Overview
11.7.3 Novartis Nucleic Acid-based Therapy Product Features and Attributes
11.7.4 Novartis Nucleic Acid-based Therapy Revenue and Gross Margin (2020-2025)
11.7.5 Novartis Recent Developments
11.8 BioNTech
11.8.1 BioNTech Corporation Information
11.8.2 BioNTech Business Overview
11.8.3 BioNTech Nucleic Acid-based Therapy Product Features and Attributes
11.8.4 BioNTech Nucleic Acid-based Therapy Revenue and Gross Margin (2020-2025)
11.8.5 BioNTech Recent Developments
11.9 Pfizer
11.9.1 Pfizer Corporation Information
11.9.2 Pfizer Business Overview
11.9.3 Pfizer Nucleic Acid-based Therapy Product Features and Attributes
11.9.4 Pfizer Nucleic Acid-based Therapy Revenue and Gross Margin (2020-2025)
11.9.5 Pfizer Recent Developments
11.10 Moderna Therapeutics
11.10.1 Moderna Therapeutics Corporation Information
11.10.2 Moderna Therapeutics Business Overview
11.10.3 Moderna Therapeutics Nucleic Acid-based Therapy Product Features and Attributes
11.10.4 Moderna Therapeutics Nucleic Acid-based Therapy Revenue and Gross Margin (2020-2025)
11.10.5 Company Ten Recent Developments
11.11 Jazz Pharmaceuticals
11.11.1 Jazz Pharmaceuticals Corporation Information
11.11.2 Jazz Pharmaceuticals Business Overview
11.11.3 Jazz Pharmaceuticals Nucleic Acid-based Therapy Product Features and Attributes
11.11.4 Jazz Pharmaceuticals Nucleic Acid-based Therapy Revenue and Gross Margin (2020-2025)
11.11.5 Jazz Pharmaceuticals Recent Developments
11.12 CureVac
11.12.1 CureVac Corporation Information
11.12.2 CureVac Business Overview
11.12.3 CureVac Nucleic Acid-based Therapy Product Features and Attributes
11.12.4 CureVac Nucleic Acid-based Therapy Revenue and Gross Margin (2020-2025)
11.12.5 CureVac Recent Developments
11.13 Regulus Therapeutics
11.13.1 Regulus Therapeutics Corporation Information
11.13.2 Regulus Therapeutics Business Overview
11.13.3 Regulus Therapeutics Nucleic Acid-based Therapy Product Features and Attributes
11.13.4 Regulus Therapeutics Nucleic Acid-based Therapy Revenue and Gross Margin (2020-2025)
11.13.5 Regulus Therapeutics Recent Developments
11.14 ProQR
11.14.1 ProQR Corporation Information
11.14.2 ProQR Business Overview
11.14.3 ProQR Nucleic Acid-based Therapy Product Features and Attributes
11.14.4 ProQR Nucleic Acid-based Therapy Revenue and Gross Margin (2020-2025)
11.14.5 ProQR Recent Developments
11.15 Secarna
11.15.1 Secarna Corporation Information
11.15.2 Secarna Business Overview
11.15.3 Secarna Nucleic Acid-based Therapy Product Features and Attributes
11.15.4 Secarna Nucleic Acid-based Therapy Revenue and Gross Margin (2020-2025)
11.15.5 Secarna Recent Developments
11.16 MiNA Therapeutics
11.16.1 MiNA Therapeutics Corporation Information
11.16.2 MiNA Therapeutics Business Overview
11.16.3 MiNA Therapeutics Nucleic Acid-based Therapy Product Features and Attributes
11.16.4 MiNA Therapeutics Nucleic Acid-based Therapy Revenue and Gross Margin (2020-2025)
11.16.5 MiNA Therapeutics Recent Developments
11.17 Sylentis
11.17.1 Sylentis Corporation Information
11.17.2 Sylentis Business Overview
11.17.3 Sylentis Nucleic Acid-based Therapy Product Features and Attributes
11.17.4 Sylentis Nucleic Acid-based Therapy Revenue and Gross Margin (2020-2025)
11.17.5 Sylentis Recent Developments
11.18 Arrowhead
11.18.1 Arrowhead Corporation Information
11.18.2 Arrowhead Business Overview
11.18.3 Arrowhead Nucleic Acid-based Therapy Product Features and Attributes
11.18.4 Arrowhead Nucleic Acid-based Therapy Revenue and Gross Margin (2020-2025)
11.18.5 Arrowhead Recent Developments
11.19 Silence Therapeutics
11.19.1 Silence Therapeutics Corporation Information
11.19.2 Silence Therapeutics Business Overview
11.19.3 Silence Therapeutics Nucleic Acid-based Therapy Product Features and Attributes
11.19.4 Silence Therapeutics Nucleic Acid-based Therapy Revenue and Gross Margin (2020-2025)
11.19.5 Silence Therapeutics Recent Developments
11.20 Dicerna
11.20.1 Dicerna Corporation Information
11.20.2 Dicerna Business Overview
11.20.3 Dicerna Nucleic Acid-based Therapy Product Features and Attributes
11.20.4 Dicerna Nucleic Acid-based Therapy Revenue and Gross Margin (2020-2025)
11.20.5 Dicerna Recent Developments
12 Nucleic Acid-based TherapyIndustry Chain Analysis
12.1 Nucleic Acid-based Therapy Industry Chain
12.2 Upstream Analysis
12.2.1 Upstream Key Suppliers
12.3 Middlestream Analysis
12.4 Downstream Sales Model and Distribution Networks
12.4.1 Sales Channels
12.4.2 Distributors
13 Nucleic Acid-based Therapy Market Dynamics
13.1 Industry Trends and Evolution
13.2 Market Growth Drivers and Emerging Opportunities
13.3 Market Challenges, Risks, and Restraints
14 Key Findings in the Global Nucleic Acid-based Therapy Study
15 Appendix
15.1 Research Methodology
15.1.1 Methodology/Research Approach
15.1.1.1 Research Programs/Design
15.1.1.2 Market Size Estimation
15.1.1.3 Market Breakdown and Data Triangulation
15.1.2 Data Source
15.1.2.1 Secondary Sources
15.1.2.2 Primary Sources
15.2 Author Details
List of Tables
 Table 1. Global Nucleic Acid-based Therapy Market Size Growth Rate by Type, 2020 VS 2024 VS 2031 (US$ Million)
 Table 2. Global Nucleic Acid-based Therapy Market Size Growth Rate by Application, 2020 VS 2024 VS 2031 (US$ Million)
 Table 3. Global Nucleic Acid-based Therapy Revenue Grow Rate (CAGR) by Region: 2020 VS 2024 VS 2031 (US$ Million)
 Table 4. Global Nucleic Acid-based Therapy Revenue by Region (2020-2025) & (US$ Million)
 Table 5. Global Nucleic Acid-based Therapy Revenue by Region (2026-2031) & (US$ Million)
 Table 6. Emerging Market Revenue Grow Rate (CAGR) by Country (2020 VS 2024 VS 2031) (US$ Million)
 Table 7. Global Nucleic Acid-based Therapy Revenue by Players (2020-2025) & (US$ Million)
 Table 8. Global Nucleic Acid-based Therapy Revenue Market Share by Players (2020-2025)
 Table 9. Global Key Players’Ranking Shift (2023 vs. 2024) (Based on Revenue)
 Table 10. Global Nucleic Acid-based Therapy by Player Tier (Tier 1, Tier 2, and Tier 3) & (based on the Revenue in Nucleic Acid-based Therapy as of 2024)
 Table 11. Global Nucleic Acid-based Therapy Average Gross Margin (%) by Player (2020 VS 2024)
 Table 12. Global Nucleic Acid-based Therapy Companies Headquarters
 Table 13. Global Nucleic Acid-based Therapy Market Concentration Ratio (CR5 and HHI)
 Table 14. Key Market Entrant/Exit (2020-2024) – Drivers & Impact Analysis
 Table 15. Key Mergers & Acquisitions, Expansion Plans, R&D Investment
 Table 16. Global Nucleic Acid-based Therapy Revenue by Type (2020-2025) & (US$ Million)
 Table 17. Global Nucleic Acid-based Therapy Revenue by Type (2026-2031) & (US$ Million)
 Table 18. Key Product Attributes and Differentiation
 Table 19. Global Nucleic Acid-based Therapy Revenue by Application (2020-2025) & (US$ Million)
 Table 20. Global Nucleic Acid-based Therapy Revenue by Application (2026-2031) & (US$ Million)
 Table 21. Nucleic Acid-based Therapy High-Growth Sectors Demand CAGR (2024-2031)
 Table 22. Top Customers by Region
 Table 23. Top Customers by Application
 Table 24. North America Nucleic Acid-based Therapy Growth Accelerators and Market Barriers
 Table 25. North America Nucleic Acid-based Therapy Revenue Grow Rate (CAGR) by Country (2020 VS 2024 VS 2031) (US$ Million)
 Table 26. Europe Nucleic Acid-based Therapy Growth Accelerators and Market Barriers
 Table 27. Europe Nucleic Acid-based Therapy Revenue Grow Rate (CAGR) by Country: 2020 VS 2024 VS 2031 (US$ Million)
 Table 28. Asia-Pacific Nucleic Acid-based Therapy Growth Accelerators and Market Barriers
 Table 29. Asia-Pacific Nucleic Acid-based Therapy Revenue Grow Rate (CAGR) by Region: 2020 VS 2024 VS 2031 (US$ Million)
 Table 30. Central and South America Nucleic Acid-based Therapy Investment Opportunities and Key Challenges
 Table 31. Central and South America Nucleic Acid-based Therapy Revenue Grow Rate (CAGR) by Country (2020 VS 2024 VS 2031) (US$ Million)
 Table 32. Middle East and Africa Nucleic Acid-based Therapy Investment Opportunities and Key Challenges
 Table 33. Middle East and Africa Nucleic Acid-based Therapy Revenue Grow Rate (CAGR) by Country (2020 VS 2024 VS 2031) (US$ Million)
 Table 34. Sarepta Therapeutics Corporation Information
 Table 35. Sarepta Therapeutics Description and Major Businesses
 Table 36. Sarepta Therapeutics Product Features and Attributes
 Table 37. Sarepta Therapeutics Revenue (US$ Million) and Gross Margin (2020-2025)
 Table 38. Sarepta Therapeutics Revenue Proportion by Product in 2024
 Table 39. Sarepta Therapeutics Revenue Proportion by Application in 2024
 Table 40. Sarepta Therapeutics Revenue Proportion by Geographic Area in 2024
 Table 41. Sarepta Therapeutics Nucleic Acid-based Therapy SWOT Analysis
 Table 42. Sarepta Therapeutics Recent Developments
 Table 43. Ionis Pharmaceuticals Corporation Information
 Table 44. Ionis Pharmaceuticals Description and Major Businesses
 Table 45. Ionis Pharmaceuticals Product Features and Attributes
 Table 46. Ionis Pharmaceuticals Revenue (US$ Million) and Gross Margin (2020-2025)
 Table 47. Ionis Pharmaceuticals Revenue Proportion by Product in 2024
 Table 48. Ionis Pharmaceuticals Revenue Proportion by Application in 2024
 Table 49. Ionis Pharmaceuticals Revenue Proportion by Geographic Area in 2024
 Table 50. Ionis Pharmaceuticals Nucleic Acid-based Therapy SWOT Analysis
 Table 51. Ionis Pharmaceuticals Recent Developments
 Table 52. Alnylam Corporation Information
 Table 53. Alnylam Description and Major Businesses
 Table 54. Alnylam Product Features and Attributes
 Table 55. Alnylam Revenue (US$ Million) and Gross Margin (2020-2025)
 Table 56. Alnylam Revenue Proportion by Product in 2024
 Table 57. Alnylam Revenue Proportion by Application in 2024
 Table 58. Alnylam Revenue Proportion by Geographic Area in 2024
 Table 59. Alnylam Nucleic Acid-based Therapy SWOT Analysis
 Table 60. Alnylam Recent Developments
 Table 61. Biogen Corporation Information
 Table 62. Biogen Description and Major Businesses
 Table 63. Biogen Product Features and Attributes
 Table 64. Biogen Revenue (US$ Million) and Gross Margin (2020-2025)
 Table 65. Biogen Revenue Proportion by Product in 2024
 Table 66. Biogen Revenue Proportion by Application in 2024
 Table 67. Biogen Revenue Proportion by Geographic Area in 2024
 Table 68. Biogen Nucleic Acid-based Therapy SWOT Analysis
 Table 69. Biogen Recent Developments
 Table 70. Nippon Shinyaku Corporation Information
 Table 71. Nippon Shinyaku Description and Major Businesses
 Table 72. Nippon Shinyaku Product Features and Attributes
 Table 73. Nippon Shinyaku Revenue (US$ Million) and Gross Margin (2020-2025)
 Table 74. Nippon Shinyaku Revenue Proportion by Product in 2024
 Table 75. Nippon Shinyaku Revenue Proportion by Application in 2024
 Table 76. Nippon Shinyaku Revenue Proportion by Geographic Area in 2024
 Table 77. Nippon Shinyaku Nucleic Acid-based Therapy SWOT Analysis
 Table 78. Nippon Shinyaku Recent Developments
 Table 79. Sobi Corporation Information
 Table 80. Sobi Description and Major Businesses
 Table 81. Sobi Product Features and Attributes
 Table 82. Sobi Revenue (US$ Million) and Gross Margin (2020-2025)
 Table 83. Sobi Recent Developments
 Table 84. Novartis Corporation Information
 Table 85. Novartis Description and Major Businesses
 Table 86. Novartis Product Features and Attributes
 Table 87. Novartis Revenue (US$ Million) and Gross Margin (2020-2025)
 Table 88. Novartis Recent Developments
 Table 89. BioNTech Corporation Information
 Table 90. BioNTech Description and Major Businesses
 Table 91. BioNTech Product Features and Attributes
 Table 92. BioNTech Revenue (US$ Million) and Gross Margin (2020-2025)
 Table 93. BioNTech Recent Developments
 Table 94. Pfizer Corporation Information
 Table 95. Pfizer Description and Major Businesses
 Table 96. Pfizer Product Features and Attributes
 Table 97. Pfizer Revenue (US$ Million) and Gross Margin (2020-2025)
 Table 98. Pfizer Recent Developments
 Table 99. Moderna Therapeutics Corporation Information
 Table 100. Moderna Therapeutics Description and Major Businesses
 Table 101. Moderna Therapeutics Product Features and Attributes
 Table 102. Moderna Therapeutics Revenue (US$ Million) and Gross Margin (2020-2025)
 Table 103. Moderna Therapeutics Recent Developments
 Table 104. Jazz Pharmaceuticals Corporation Information
 Table 105. Jazz Pharmaceuticals Description and Major Businesses
 Table 106. Jazz Pharmaceuticals Product Features and Attributes
 Table 107. Jazz Pharmaceuticals Revenue (US$ Million) and Gross Margin (2020-2025)
 Table 108. Jazz Pharmaceuticals Recent Developments
 Table 109. CureVac Corporation Information
 Table 110. CureVac Description and Major Businesses
 Table 111. CureVac Product Features and Attributes
 Table 112. CureVac Revenue (US$ Million) and Gross Margin (2020-2025)
 Table 113. CureVac Recent Developments
 Table 114. Regulus Therapeutics Corporation Information
 Table 115. Regulus Therapeutics Description and Major Businesses
 Table 116. Regulus Therapeutics Product Features and Attributes
 Table 117. Regulus Therapeutics Revenue (US$ Million) and Gross Margin (2020-2025)
 Table 118. Regulus Therapeutics Recent Developments
 Table 119. ProQR Corporation Information
 Table 120. ProQR Description and Major Businesses
 Table 121. ProQR Product Features and Attributes
 Table 122. ProQR Revenue (US$ Million) and Gross Margin (2020-2025)
 Table 123. ProQR Recent Developments
 Table 124. Secarna Corporation Information
 Table 125. Secarna Description and Major Businesses
 Table 126. Secarna Product Features and Attributes
 Table 127. Secarna Revenue (US$ Million) and Gross Margin (2020-2025)
 Table 128. Secarna Recent Developments
 Table 129. MiNA Therapeutics Corporation Information
 Table 130. MiNA Therapeutics Description and Major Businesses
 Table 131. MiNA Therapeutics Product Features and Attributes
 Table 132. MiNA Therapeutics Revenue (US$ Million) and Gross Margin (2020-2025)
 Table 133. MiNA Therapeutics Recent Developments
 Table 134. Sylentis Corporation Information
 Table 135. Sylentis Description and Major Businesses
 Table 136. Sylentis Product Features and Attributes
 Table 137. Sylentis Revenue (US$ Million) and Gross Margin (2020-2025)
 Table 138. Sylentis Recent Developments
 Table 139. Arrowhead Corporation Information
 Table 140. Arrowhead Description and Major Businesses
 Table 141. Arrowhead Product Features and Attributes
 Table 142. Arrowhead Revenue (US$ Million) and Gross Margin (2020-2025)
 Table 143. Arrowhead Recent Developments
 Table 144. Silence Therapeutics Corporation Information
 Table 145. Silence Therapeutics Description and Major Businesses
 Table 146. Silence Therapeutics Product Features and Attributes
 Table 147. Silence Therapeutics Revenue (US$ Million) and Gross Margin (2020-2025)
 Table 148. Silence Therapeutics Recent Developments
 Table 149. Dicerna Corporation Information
 Table 150. Dicerna Description and Major Businesses
 Table 151. Dicerna Product Features and Attributes
 Table 152. Dicerna Revenue (US$ Million) and Gross Margin (2020-2025)
 Table 153. Dicerna Recent Developments
 Table 154. Raw Materials Key Suppliers
 Table 155. Distributors List
 Table 156. Market Trends and Market Evolution
 Table 157. Market Drivers and Opportunities
 Table 158. Market Challenges, Risks, and Restraints
 Table 159. Research Programs/Design for This Report
 Table 160. Key Data Information from Secondary Sources
 Table 161. Key Data Information from Primary Sources


List of Figures
 Figure 1. Nucleic Acid-based Therapy Product Picture
 Figure 2. Global Nucleic Acid-based Therapy Market Size Growth Rate by Type, 2020 VS 2024 VS 2031 (US$ Million)
 Figure 3. Antisense Oligonucleotides (ASO) Product Picture
 Figure 4. siRNA Product Picture
 Figure 5. mRNA Product Picture
 Figure 6. Global Nucleic Acid-based Therapy Market Size Growth Rate by Application, 2020 VS 2024 VS 2031 (US$ Million)
 Figure 7. Neuromuscular Diseases
 Figure 8. hATTR
 Figure 9. COVID-19
 Figure 10. Other
 Figure 11. Nucleic Acid-based Therapy Report Years Considered
 Figure 12. Global Nucleic Acid-based Therapy Revenue, (US$ Million), 2020 VS 2024 VS 2031
 Figure 13. Global Nucleic Acid-based Therapy Revenue (2020-2031) & (US$ Million)
 Figure 14. Global Nucleic Acid-based Therapy Revenue (CAGR) by Region: 2020 VS 2024 VS 2031 (US$ Million)
 Figure 15. Global Nucleic Acid-based Therapy Revenue Market Share by Region (2020-2031)
 Figure 16. Global Nucleic Acid-based Therapy Revenue Market Share Ranking (2024)
 Figure 17. Tier Distribution by Revenue Contribution (2020 VS 2024)
 Figure 18. Antisense Oligonucleotides (ASO) Revenue Market Share by Player in 2024
 Figure 19. siRNA Revenue Market Share by Player in 2024
 Figure 20. mRNA Revenue Market Share by Player in 2024
 Figure 21. Global Nucleic Acid-based Therapy Revenue Market Share by Type (2020-2031)
 Figure 22. Global Nucleic Acid-based Therapy Revenue Market Share by Application (2020-2031)
 Figure 23. North America Nucleic Acid-based Therapy Revenue YoY (2020-2031) & (US$ Million)
 Figure 24. North America Top 5 Players Nucleic Acid-based Therapy Revenue (US$ Million) in 2024
 Figure 25. North America Nucleic Acid-based Therapy Revenue (US$ Million) by Type (2020 - 2031)
 Figure 26. North America Nucleic Acid-based Therapy Revenue (US$ Million) by Application (2020-2031)
 Figure 27. US Nucleic Acid-based Therapy Revenue (2020-2031) & (US$ Million)
 Figure 28. Canada Nucleic Acid-based Therapy Revenue (2020-2031) & (US$ Million)
 Figure 29. Mexico Nucleic Acid-based Therapy Revenue (2020-2031) & (US$ Million)
 Figure 30. Europe Nucleic Acid-based Therapy Revenue YoY (2020-2031) & (US$ Million)
 Figure 31. Europe Top 5 Players Nucleic Acid-based Therapy Revenue (US$ Million) in 2024
 Figure 32. Europe Nucleic Acid-based Therapy Revenue (US$ Million) by Type (2020-2031)
 Figure 33. Europe Nucleic Acid-based Therapy Revenue (US$ Million) by Application (2020-2031)
 Figure 34. Germany Nucleic Acid-based Therapy Revenue (2020-2031) & (US$ Million)
 Figure 35. France Nucleic Acid-based Therapy Revenue (2020-2031) & (US$ Million)
 Figure 36. U.K. Nucleic Acid-based Therapy Revenue (2020-2031) & (US$ Million)
 Figure 37. Italy Nucleic Acid-based Therapy Revenue (2020-2031) & (US$ Million)
 Figure 38. Russia Nucleic Acid-based Therapy Revenue (2020-2031) & (US$ Million)
 Figure 39. Asia-Pacific Nucleic Acid-based Therapy Revenue YoY (2020-2031) & (US$ Million)
 Figure 40. Asia-Pacific Top 8 Players Nucleic Acid-based Therapy Revenue (US$ Million) in 2024
 Figure 41. Asia-Pacific Nucleic Acid-based Therapy Revenue (US$ Million) by Type (2020-2031)
 Figure 42. Asia-Pacific Nucleic Acid-based Therapy Revenue (US$ Million) by Application (2020-2031)
 Figure 43. Indonesia Nucleic Acid-based Therapy Revenue (2020-2031) & (US$ Million)
 Figure 44. Japan Nucleic Acid-based Therapy Revenue (2020-2031) & (US$ Million)
 Figure 45. South Korea Nucleic Acid-based Therapy Revenue (2020-2031) & (US$ Million)
 Figure 46. Australia Nucleic Acid-based Therapy Revenue (2020-2031) & (US$ Million)
 Figure 47. India Nucleic Acid-based Therapy Revenue (2020-2031) & (US$ Million)
 Figure 48. Indonesia Nucleic Acid-based Therapy Revenue (2020-2031) & (US$ Million)
 Figure 49. Vietnam Nucleic Acid-based Therapy Revenue (2020-2031) & (US$ Million)
 Figure 50. Malaysia Nucleic Acid-based Therapy Revenue (2020-2031) & (US$ Million)
 Figure 51. Philippines Nucleic Acid-based Therapy Revenue (2020-2031) & (US$ Million)
 Figure 52. Singapore Nucleic Acid-based Therapy Revenue (2020-2031) & (US$ Million)
 Figure 53. Central and South America Nucleic Acid-based Therapy Revenue YoY (2020-2031) & (US$ Million)
 Figure 54. Central and South America Top 5 Players Nucleic Acid-based Therapy Revenue (US$ Million) in 2024
 Figure 55. Central and South America Nucleic Acid-based Therapy Revenue (US$ Million) by Type (2020-2031)
 Figure 56. Central and South America Nucleic Acid-based Therapy Revenue (US$ Million) by Application (2020-2031)
 Figure 57. Brazil Nucleic Acid-based Therapy Revenue (2020-2025) & (US$ Million)
 Figure 58. Argentina Nucleic Acid-based Therapy Revenue (2020-2025) & (US$ Million)
 Figure 59. Middle East and Africa Nucleic Acid-based Therapy Revenue YoY (2020-2031) & (US$ Million)
 Figure 60. Middle East and Africa Top 5 Players Nucleic Acid-based Therapy Revenue (US$ Million) in 2024
 Figure 61. South America Nucleic Acid-based Therapy Revenue (US$ Million) by Type (2020-2031)
 Figure 62. Middle East and Africa Nucleic Acid-based Therapy Revenue (US$ Million) by Application (2020-2031)
 Figure 63. GCC Countries Nucleic Acid-based Therapy Revenue (2020-2025) & (US$ Million)
 Figure 64. Israel Nucleic Acid-based Therapy Revenue (2020-2025) & (US$ Million)
 Figure 65. Egypt Nucleic Acid-based Therapy Revenue (2020-2025) & (US$ Million)
 Figure 66. South Africa Nucleic Acid-based Therapy Revenue (2020-2025) & (US$ Million)
 Figure 67. Nucleic Acid-based Therapy Industry Chain Mapping
 Figure 68. Channels of Distribution (Direct Vs Distribution)
 Figure 69. Bottom-up and Top-down Approaches for This Report
 Figure 70. Data Triangulation
 Figure 71. Key Executives Interviewed
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