The global market for Vitamin K–Dependent Coagulation Factor Complex was valued at US$ 1324 million in the year 2024 and is projected to reach a revised size of US$ 2652 million by 2031, growing at a CAGR of 10.4% during the forecast period.

Vitamin K–Dependent Coagulation Factor Complex Market

The 2025 U.S. tariff policies introduce profound uncertainty into the global economic landscape. This report critically examines the implications of recent tariff adjustments and international strategic countermeasures on Vitamin K–Dependent Coagulation Factor Complex competitive dynamics, regional economic interdependencies, and supply chain reconfigurations.

The Vitamin K–Dependent Coagulation Factor Complex (commonly marketed and used clinically as Prothrombin Complex Concentrate, PCC) is a plasma-derived therapeutic containing coagulation factors II, VII, IX, and X, along with variable amounts of other vitamin K-dependent proteins. It is designed to rapidly restore or replace these factors in patients to halt severe bleeding or to reverse the anticoagulant effects of vitamin K antagonists such as warfarin. PCC formulations are available as three-factor or four-factor products and play a critical role in emergency hemorrhage control, perioperative anticoagulation reversal, and replacement therapy for certain congenital or acquired factor deficiencies. Advances in bioprocessing, viral inactivation, and cold-chain logistics have markedly improved the safety, batch consistency, and traceability of modern PCCs, enabling their wider adoption in acute care and specialty hematology settings. Clearer clinical indications, growing guideline recognition, and ongoing industry investment have accelerated the evolution of PCCs from traditional plasma derivatives to highly standardized pharmaceutical products. In 2024, global Vitamin K–Dependent Coagulation Factor Complex production reached approximately 4.27 m units, with an average global market price of around US$ 310 perunit.The average gross profit margin of this product is 65%.

The market for Vitamin K–Dependent Coagulation Factor Complexes has entered a phase of structural growth: robust emergency and perioperative needs for anticoagulation reversal, alongside clearer guideline and clinical consensus favoring rapid and predictable factor replacement, are accelerating hospital shifts from traditional fresh frozen plasma toward standardized PCC products. Continued industry investment in modern bioprocessing, viral safety, and traceability systems has materially improved PCC accessibility and clinician confidence. Increased collaborations between specialty centers and manufacturers to generate clinical evidence and expand labeled indications are further consolidating clinical pathways for PCC use, creating sustained opportunities across tertiary hospitals, emergency departments, and major surgical centers.

Despite clear opportunities, the sector faces multiple risks including regulatory compliance, supply-chain fragility, and intensifying competition. As plasma-derived biologics, PCCs require stringent control of plasma quality, batch consistency, and viral safety—any supplier disruption or quality incident can markedly impact market trust and regulatory scrutiny. Heterogeneous registration and reimbursement frameworks across regions complicate global commercialization. Moreover, emerging alternatives—such as recombinant factor products, gene therapies, or biosimilars—may reshape long-term competition and compress traditional value cushions.

Downstream demand trends toward clinical standardization, stratification, and evidence-driven use: hospitals increasingly prefer agents that rapidly restore hemostasis to reduce ICU stays and complication rates; perioperative and emergency settings account for growing shares of utilization, while specialty clinics define clearer needs for replacement therapy. Purchasing decisions increasingly prioritize clinical evidence, supply stability, and total cost of ownership (including storage and administration convenience). Regional health systems developing anticoagulation reversal pathways tend to favor PCC products that balance safety with operational efficiency, benefiting high-quality suppliers.

The upstream backbone is human plasma, with source control spanning donor screening, plasma collection networks, initial processing, and viral inactivation. Raw material availability depends on the maturity of national donor systems, regulatory regimes, and seasonality; firms with vertically integrated or long-term procurement arrangements hold clear advantages in cost and supply reliability. At the same time, manufacturers are pursuing process intensification, scale economies, and alternative production modalities (including recombinant or synthetic biology approaches) to partially de-risk plasma dependence and improve batch consistency. Environmental and sustainability expectations have elevated provenance, compliance proof, and ecological stewardship into competitive upstream criteria.

Report Scope

This report aims to provide a comprehensive presentation of the global market for Vitamin K–Dependent Coagulation Factor Complex, with both quantitative and qualitative analysis, to help readers develop business/growth strategies, assess the market competitive situation, analyze their position in the current marketplace, and make informed business decisions regarding Vitamin K–Dependent Coagulation Factor Complex.

The Vitamin K–Dependent Coagulation Factor Complex market size, estimations, and forecasts are provided in terms of sales volume (K Units) and revenue ($ millions), considering 2024 as the base year, with history and forecast data for the period from 2020 to 2031. This report segments the global Vitamin K–Dependent Coagulation Factor Complex market comprehensively. Regional market sizes, concerning products by Type, by Application, by Product Type and by players, are also provided.

For a more in-depth understanding of the market, the report provides profiles of the competitive landscape, key competitors, and their respective market ranks. The report also discusses technological trends and new product developments.

The report will help the Vitamin K–Dependent Coagulation Factor Complex manufacturers, new entrants, and industry chain related companies in this market with information on the revenues, sales volume, and average price for the overall market and the sub-segments across the different segments, by company, by Type, by Application, by Product Type and by regions.

Scope of Vitamin K–Dependent Coagulation Factor Complex Market Report

Report Metric	Details
Report Name	Vitamin K–Dependent Coagulation Factor Complex Market
Accounted market size in year	US$ 1324 million
Forecasted market size in 2031	US$ 2652 million
CAGR	10.4%
Base Year	year
Forecasted years	2025 - 2031
Segment by Type	Beriplex Profilnine Octaplex Prothromplex Cofact Other
Segment by Product Type	3-Factor PCC 4-Factor PCC Recombinant Coagulation Complex Other
Segment by Source	Plasma-Derived Recombinant Bioengineered
Segment by Dosage Form	Lyophilized Powder for Injection Liquid Formulation
Segment by Application	Hemophilia B Acquired Coagulation Factor Deficiency
Consumption by Region	North America (United States, Canada) Europe (Germany, France, UK, Italy, Russia) Asia-Pacific (China, Japan, South Korea, Taiwan) Southeast Asia (India) Latin America (Mexico, Brazil)
By Company	CSL Behring, Grifols, Octapharma, Prothya Biosolutions, Takeda, Biotest, Hualan Biological
Forecast units	USD million in value
Report coverage	Revenue and volume forecast, company share, competitive landscape, growth factors and trends

Core Chapters

Chapter 1: Introduces the report scope of the report, executive summary of different market segments (by region, product type, application, etc), including the market size of each market segment, future development potential, and so on. It offers a high-level view of the current state of the market and its likely evolution in the short to mid-term, and long term.
Chapter 2: Detailed analysis of Vitamin K–Dependent Coagulation Factor Complex manufacturers competitive landscape, price, sales and revenue market share, latest development plan, merger, and acquisition information, etc.
Chapter 3: Sales, revenue of Vitamin K–Dependent Coagulation Factor Complex in regional level and country level. It provides a quantitative analysis of the market size and development potential of each region and its main countries and introduces the market development, future development prospects, market space, and market size of each country in the world.
Chapter 4: Provides the analysis of various market segments by Type, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different market segments.
Chapter 5: Provides the analysis of various market segments by Application, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different downstream markets.
Chapter 6: Provides profiles of key players, introducing the basic situation of the main companies in the market in detail, including product sales, revenue, price, gross margin, product introduction, recent development, etc.
Chapter 7: Analysis of industrial chain, including the upstream and downstream of the industry.
Chapter 8: Introduces the market dynamics, latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by manufacturers in the industry, and the analysis of relevant policies in the industry.
Chapter 9: The main points and conclusions of the report.

FAQ for this report

How fast is Vitamin K–Dependent Coagulation Factor Complex Market growing?

Ans: The Vitamin K–Dependent Coagulation Factor Complex Market witnessing a CAGR of 10.4% during the forecast period 2025-2031.

What is the Vitamin K–Dependent Coagulation Factor Complex Market size in 2031?

Ans: The Vitamin K–Dependent Coagulation Factor Complex Market size in 2031 will be US$ 2652 million.

Who are the main players in the Vitamin K–Dependent Coagulation Factor Complex Market report?

Ans: The main players in the Vitamin K–Dependent Coagulation Factor Complex Market are CSL Behring, Grifols, Octapharma, Prothya Biosolutions, Takeda, Biotest, Hualan Biological

What are the Application segmentation covered in the Vitamin K–Dependent Coagulation Factor Complex Market report?

Ans: The Applications covered in the Vitamin K–Dependent Coagulation Factor Complex Market report are Hemophilia B, Acquired Coagulation Factor Deficiency

What are the Type segmentation covered in the Vitamin K–Dependent Coagulation Factor Complex Market report?

Ans: The Types covered in the Vitamin K–Dependent Coagulation Factor Complex Market report are 3-Factor PCC, 4-Factor PCC, Recombinant Coagulation Complex, Other

1 Vitamin K–Dependent Coagulation Factor Complex Market Overview

1.1 Product Definition

1.2 Vitamin K–Dependent Coagulation Factor Complex by Type

1.2.1 Global Vitamin K–Dependent Coagulation Factor Complex Market Value Comparison by Type (2024 VS 2031)

1.2.2 Beriplex

1.2.3 Profilnine

1.2.4 Octaplex

1.2.5 Prothromplex

1.2.6 Cofact

1.2.7 Other

1.3 Vitamin K–Dependent Coagulation Factor Complex by Product Type

1.3.1 Global Vitamin K–Dependent Coagulation Factor Complex Market Value Comparison by Product Type: 2024 VS 2031

1.3.2 3-Factor PCC

1.3.3 4-Factor PCC

1.3.4 Recombinant Coagulation Complex

1.3.5 Other

1.4 Vitamin K–Dependent Coagulation Factor Complex by Source

1.4.1 Global Vitamin K–Dependent Coagulation Factor Complex Market Value Comparison by Source: 2024 VS 2031

1.4.2 Plasma-Derived

1.4.3 Recombinant Bioengineered

1.5 Vitamin K–Dependent Coagulation Factor Complex by Dosage Form

1.5.1 Global Vitamin K–Dependent Coagulation Factor Complex Market Value Comparison by Dosage Form: 2024 VS 2031

1.5.2 Lyophilized Powder for Injection

1.5.3 Liquid Formulation

1.6 Vitamin K–Dependent Coagulation Factor Complex by Application

1.6.1 Global Vitamin K–Dependent Coagulation Factor Complex Market Value by Application (2024 VS 2031)

1.6.2 Hemophilia B

1.6.3 Acquired Coagulation Factor Deficiency

1.7 Global Vitamin K–Dependent Coagulation Factor Complex Market Size Estimates and Forecasts

1.7.1 Global Vitamin K–Dependent Coagulation Factor Complex Revenue 2020-2031

1.7.2 Global Vitamin K–Dependent Coagulation Factor Complex Sales 2020-2031

1.7.3 Global Vitamin K–Dependent Coagulation Factor Complex Market Average Price (2020-2031)

1.8 Assumptions and Limitations

2 Vitamin K–Dependent Coagulation Factor Complex Market Competition by Manufacturers

2.1 Global Vitamin K–Dependent Coagulation Factor Complex Sales Market Share by Manufacturers (2020-2025)

2.2 Global Vitamin K–Dependent Coagulation Factor Complex Revenue Market Share by Manufacturers (2020-2025)

2.3 Global Vitamin K–Dependent Coagulation Factor Complex Average Price by Manufacturers (2020-2025)

2.4 Global Key Players of Vitamin K–Dependent Coagulation Factor Complex, Industry Ranking, 2022 VS 2023 VS 2024

2.5 Global Key Manufacturers of Vitamin K–Dependent Coagulation Factor Complex, Manufacturing Sites & Headquarters

2.6 Global Key Manufacturers of Vitamin K–Dependent Coagulation Factor Complex, Product Type & Application

2.7 Global Key Manufacturers of Vitamin K–Dependent Coagulation Factor Complex, Date of Enter into This Industry

2.8 Global Vitamin K–Dependent Coagulation Factor Complex Market Competitive Situation and Trends

2.8.1 Global Vitamin K–Dependent Coagulation Factor Complex Market Concentration Rate

2.8.2 The Global 5 and 10 Largest Vitamin K–Dependent Coagulation Factor Complex Players Market Share by Revenue

2.8.3 Global Vitamin K–Dependent Coagulation Factor Complex Company Type and Market Share by Company Type (Tier 1, Tier 2, and Tier 3)

2.9 Manufacturers Mergers & Acquisitions, Expansion Plans

3 Global Vitamin K–Dependent Coagulation Factor Complex Market Scenario by Region

3.1 Global Vitamin K–Dependent Coagulation Factor Complex Market Size by Region: 2020 Versus 2024 Versus 2031

3.2 Global Vitamin K–Dependent Coagulation Factor Complex Sales by Region: 2020-2031

3.2.1 Global Vitamin K–Dependent Coagulation Factor Complex Sales by Region: 2020-2025

3.2.2 Global Vitamin K–Dependent Coagulation Factor Complex Sales by Region: 2026-2031

3.3 Global Vitamin K–Dependent Coagulation Factor Complex Revenue by Region: 2020-2031

3.3.1 Global Vitamin K–Dependent Coagulation Factor Complex Revenue by Region: 2020-2025

3.3.2 Global Vitamin K–Dependent Coagulation Factor Complex Revenue by Region: 2026-2031

3.4 North America Vitamin K–Dependent Coagulation Factor Complex Market Facts & Figures by Country

3.4.1 North America Vitamin K–Dependent Coagulation Factor Complex Market Size by Country: 2020 VS 2024 VS 2031

3.4.2 North America Vitamin K–Dependent Coagulation Factor Complex Sales by Country (2020-2031)

3.4.3 North America Vitamin K–Dependent Coagulation Factor Complex Revenue by Country (2020-2031)

3.4.4 United States

3.4.5 Canada

3.5 Europe Vitamin K–Dependent Coagulation Factor Complex Market Facts & Figures by Country

3.5.1 Europe Vitamin K–Dependent Coagulation Factor Complex Market Size by Country: 2020 VS 2024 VS 2031

3.5.2 Europe Vitamin K–Dependent Coagulation Factor Complex Sales by Country (2020-2031)

3.5.3 Europe Vitamin K–Dependent Coagulation Factor Complex Revenue by Country (2020-2031)

3.5.4 Germany

3.5.5 France

3.5.6 U.K.

3.5.7 Italy

3.5.8 Russia

3.6 Asia Pacific Vitamin K–Dependent Coagulation Factor Complex Market Facts & Figures by Region

3.6.1 Asia Pacific Vitamin K–Dependent Coagulation Factor Complex Market Size by Region: 2020 VS 2024 VS 2031

3.6.2 Asia Pacific Vitamin K–Dependent Coagulation Factor Complex Sales by Region (2020-2031)

3.6.3 Asia Pacific Vitamin K–Dependent Coagulation Factor Complex Revenue by Region (2020-2031)

3.6.4 China

3.6.5 Japan

3.6.6 South Korea

3.6.7 India

3.6.8 Australia

3.6.9 China Taiwan

3.6.10 Southeast Asia

3.7 Latin America Vitamin K–Dependent Coagulation Factor Complex Market Facts & Figures by Country

3.7.1 Latin America Vitamin K–Dependent Coagulation Factor Complex Market Size by Country: 2020 VS 2024 VS 2031

3.7.2 Latin America Vitamin K–Dependent Coagulation Factor Complex Sales by Country (2020-2031)

3.7.3 Latin America Vitamin K–Dependent Coagulation Factor Complex Revenue by Country (2020-2031)

3.7.4 Mexico

3.7.5 Brazil

3.7.6 Argentina

3.8 Middle East and Africa Vitamin K–Dependent Coagulation Factor Complex Market Facts & Figures by Country

3.8.1 Middle East and Africa Vitamin K–Dependent Coagulation Factor Complex Market Size by Country: 2020 VS 2024 VS 2031

3.8.2 Middle East and Africa Vitamin K–Dependent Coagulation Factor Complex Sales by Country (2020-2031)

3.8.3 Middle East and Africa Vitamin K–Dependent Coagulation Factor Complex Revenue by Country (2020-2031)

3.8.4 Turkey

3.8.5 Saudi Arabia

3.8.6 UAE

4 Segment by Type

4.1 Global Vitamin K–Dependent Coagulation Factor Complex Sales by Type (2020-2031)

4.1.1 Global Vitamin K–Dependent Coagulation Factor Complex Sales by Type (2020-2025)

4.1.2 Global Vitamin K–Dependent Coagulation Factor Complex Sales by Type (2026-2031)

4.1.3 Global Vitamin K–Dependent Coagulation Factor Complex Sales Market Share by Type (2020-2031)

4.2 Global Vitamin K–Dependent Coagulation Factor Complex Revenue by Type (2020-2031)

4.2.1 Global Vitamin K–Dependent Coagulation Factor Complex Revenue by Type (2020-2025)

4.2.2 Global Vitamin K–Dependent Coagulation Factor Complex Revenue by Type (2026-2031)

4.2.3 Global Vitamin K–Dependent Coagulation Factor Complex Revenue Market Share by Type (2020-2031)

4.3 Global Vitamin K–Dependent Coagulation Factor Complex Price by Type (2020-2031)

5 Segment by Application

5.1 Global Vitamin K–Dependent Coagulation Factor Complex Sales by Application (2020-2031)

5.1.1 Global Vitamin K–Dependent Coagulation Factor Complex Sales by Application (2020-2025)

5.1.2 Global Vitamin K–Dependent Coagulation Factor Complex Sales by Application (2026-2031)

5.1.3 Global Vitamin K–Dependent Coagulation Factor Complex Sales Market Share by Application (2020-2031)

5.2 Global Vitamin K–Dependent Coagulation Factor Complex Revenue by Application (2020-2031)

5.2.1 Global Vitamin K–Dependent Coagulation Factor Complex Revenue by Application (2020-2025)

5.2.2 Global Vitamin K–Dependent Coagulation Factor Complex Revenue by Application (2026-2031)

5.2.3 Global Vitamin K–Dependent Coagulation Factor Complex Revenue Market Share by Application (2020-2031)

5.3 Global Vitamin K–Dependent Coagulation Factor Complex Price by Application (2020-2031)

6 Key Companies Profiled

6.1 CSL Behring

6.1.1 CSL Behring Company Information

6.1.2 CSL Behring Description and Business Overview

6.1.3 CSL Behring Vitamin K–Dependent Coagulation Factor Complex Sales, Revenue and Gross Margin (2020-2025)

6.1.4 CSL Behring Vitamin K–Dependent Coagulation Factor Complex Product Portfolio

6.1.5 CSL Behring Recent Developments/Updates

6.2 Grifols

6.2.1 Grifols Company Information

6.2.2 Grifols Description and Business Overview

6.2.3 Grifols Vitamin K–Dependent Coagulation Factor Complex Sales, Revenue and Gross Margin (2020-2025)

6.2.4 Grifols Vitamin K–Dependent Coagulation Factor Complex Product Portfolio

6.2.5 Grifols Recent Developments/Updates

6.3 Octapharma

6.3.1 Octapharma Company Information

6.3.2 Octapharma Description and Business Overview

6.3.3 Octapharma Vitamin K–Dependent Coagulation Factor Complex Sales, Revenue and Gross Margin (2020-2025)

6.3.4 Octapharma Vitamin K–Dependent Coagulation Factor Complex Product Portfolio

6.3.5 Octapharma Recent Developments/Updates

6.4 Prothya Biosolutions

6.4.1 Prothya Biosolutions Company Information

6.4.2 Prothya Biosolutions Description and Business Overview

6.4.3 Prothya Biosolutions Vitamin K–Dependent Coagulation Factor Complex Sales, Revenue and Gross Margin (2020-2025)

6.4.4 Prothya Biosolutions Vitamin K–Dependent Coagulation Factor Complex Product Portfolio

6.4.5 Prothya Biosolutions Recent Developments/Updates

6.5 Takeda

6.5.1 Takeda Company Information

6.5.2 Takeda Description and Business Overview

6.5.3 Takeda Vitamin K–Dependent Coagulation Factor Complex Sales, Revenue and Gross Margin (2020-2025)

6.5.4 Takeda Vitamin K–Dependent Coagulation Factor Complex Product Portfolio

6.5.5 Takeda Recent Developments/Updates

6.6 Biotest

6.6.1 Biotest Company Information

6.6.2 Biotest Description and Business Overview

6.6.3 Biotest Vitamin K–Dependent Coagulation Factor Complex Sales, Revenue and Gross Margin (2020-2025)

6.6.4 Biotest Vitamin K–Dependent Coagulation Factor Complex Product Portfolio

6.6.5 Biotest Recent Developments/Updates

6.7 Hualan Biological

6.7.1 Hualan Biological Company Information

6.7.2 Hualan Biological Description and Business Overview

6.7.3 Hualan Biological Vitamin K–Dependent Coagulation Factor Complex Sales, Revenue and Gross Margin (2020-2025)

6.7.4 Hualan Biological Vitamin K–Dependent Coagulation Factor Complex Product Portfolio

6.7.5 Hualan Biological Recent Developments/Updates

7 Industry Chain and Sales Channels Analysis

7.1 Vitamin K–Dependent Coagulation Factor Complex Industry Chain Analysis

7.2 Vitamin K–Dependent Coagulation Factor Complex Raw Material Supply Analysis

7.2.1 Key Raw Materials

7.2.2 Raw Materials Key Suppliers

7.3 Vitamin K–Dependent Coagulation Factor Complex Production Mode & Process Analysis

7.4 Vitamin K–Dependent Coagulation Factor Complex Sales and Marketing

7.4.1 Vitamin K–Dependent Coagulation Factor Complex Sales Channels

7.4.2 Vitamin K–Dependent Coagulation Factor Complex Distributors

7.5 Vitamin K–Dependent Coagulation Factor Complex Customer Analysis

8 Vitamin K–Dependent Coagulation Factor Complex Market Dynamics

8.1 Vitamin K–Dependent Coagulation Factor Complex Industry Trends

8.2 Vitamin K–Dependent Coagulation Factor Complex Market Drivers

8.3 Vitamin K–Dependent Coagulation Factor Complex Market Challenges

8.4 Vitamin K–Dependent Coagulation Factor Complex Market Restraints

9 Research Findings and Conclusion

10 Methodology and Data Source

10.1 Methodology/Research Approach

10.1.1 Research Programs/Design

10.1.2 Market Size Estimation

10.1.3 Market Breakdown and Data Triangulation

10.2 Data Source

10.2.1 Secondary Sources

10.2.2 Primary Sources

10.3 Author List

10.4 Disclaimer

FEATURED COMPANIES

List of Tables

Table 1. Global Vitamin K–Dependent Coagulation Factor Complex Market Value Comparison by Type (2024 VS 2031) & (US$ Million)

Table 2. Global Vitamin K–Dependent Coagulation Factor Complex Market Value by Product Type, (US$ Million) & (2024 VS 2031)

Table 3. Global Vitamin K–Dependent Coagulation Factor Complex Market Value by Source, (US$ Million) & (2024 VS 2031)

Table 4. Global Vitamin K–Dependent Coagulation Factor Complex Market Value by Dosage Form, (US$ Million) & (2024 VS 2031)

Table 5. Global Vitamin K–Dependent Coagulation Factor Complex Market Value by Application (2024 VS 2031) & (US$ Million)

Table 6. Global Vitamin K–Dependent Coagulation Factor Complex Market Competitive Situation by Manufacturers in 2024

Table 7. Global Vitamin K–Dependent Coagulation Factor Complex Sales (K Units) of Key Manufacturers (2020-2025)

Table 8. Global Vitamin K–Dependent Coagulation Factor Complex Sales Market Share by Manufacturers (2020-2025)

Table 9. Global Vitamin K–Dependent Coagulation Factor Complex Revenue (US$ Million) by Manufacturers (2020-2025)

Table 10. Global Vitamin K–Dependent Coagulation Factor Complex Revenue Share by Manufacturers (2020-2025)

Table 11. Global Market Vitamin K–Dependent Coagulation Factor Complex Average Price (US$/Unit) of Key Manufacturers (2020-2025)

Table 12. Global Key Players of Vitamin K–Dependent Coagulation Factor Complex, Industry Ranking, 2022 VS 2023 VS 2024

Table 13. Global Key Manufacturers of Vitamin K–Dependent Coagulation Factor Complex, Manufacturing Sites & Headquarters

Table 14. Global Key Manufacturers of Vitamin K–Dependent Coagulation Factor Complex, Product Type & Application

Table 15. Global Key Manufacturers of Vitamin K–Dependent Coagulation Factor Complex, Date of Enter into This Industry

Table 16. Global Manufacturers Market Concentration Ratio (CR5 and HHI)

Table 17. Global Vitamin K–Dependent Coagulation Factor Complex by Company Type (Tier 1, Tier 2, and Tier 3) & (based on the Revenue in Vitamin K–Dependent Coagulation Factor Complex as of 2024)

Table 18. Manufacturers Mergers & Acquisitions, Expansion Plans

Table 19. Global Vitamin K–Dependent Coagulation Factor Complex Market Size by Region (US$ Million): 2020 VS 2024 VS 2031

Table 20. Global Vitamin K–Dependent Coagulation Factor Complex Sales by Region (2020-2025) & (K Units)

Table 21. Global Vitamin K–Dependent Coagulation Factor Complex Sales Market Share by Region (2020-2025)

Table 22. Global Vitamin K–Dependent Coagulation Factor Complex Sales by Region (2026-2031) & (K Units)

Table 23. Global Vitamin K–Dependent Coagulation Factor Complex Sales Market Share by Region (2026-2031)

Table 24. Global Vitamin K–Dependent Coagulation Factor Complex Revenue by Region (2020-2025) & (US$ Million)

Table 25. Global Vitamin K–Dependent Coagulation Factor Complex Revenue Market Share by Region (2020-2025)

Table 26. Global Vitamin K–Dependent Coagulation Factor Complex Revenue by Region (2026-2031) & (US$ Million)

Table 27. Global Vitamin K–Dependent Coagulation Factor Complex Revenue Market Share by Region (2026-2031)

Table 28. North America Vitamin K–Dependent Coagulation Factor Complex Revenue by Country: 2020 VS 2024 VS 2031 (US$ Million)

Table 29. North America Vitamin K–Dependent Coagulation Factor Complex Sales by Country (2020-2025) & (K Units)

Table 30. North America Vitamin K–Dependent Coagulation Factor Complex Sales by Country (2026-2031) & (K Units)

Table 31. North America Vitamin K–Dependent Coagulation Factor Complex Revenue by Country (2020-2025) & (US$ Million)

Table 32. North America Vitamin K–Dependent Coagulation Factor Complex Revenue by Country (2026-2031) & (US$ Million)

Table 33. Europe Vitamin K–Dependent Coagulation Factor Complex Revenue by Country: 2020 VS 2024 VS 2031 (US$ Million)

Table 34. Europe Vitamin K–Dependent Coagulation Factor Complex Sales by Country (2020-2025) & (K Units)

Table 35. Europe Vitamin K–Dependent Coagulation Factor Complex Sales by Country (2026-2031) & (K Units)

Table 36. Europe Vitamin K–Dependent Coagulation Factor Complex Revenue by Country (2020-2025) & (US$ Million)

Table 37. Europe Vitamin K–Dependent Coagulation Factor Complex Revenue by Country (2026-2031) & (US$ Million)

Table 38. Asia Pacific Vitamin K–Dependent Coagulation Factor Complex Revenue by Region: 2020 VS 2024 VS 2031 (US$ Million)

Table 39. Asia Pacific Vitamin K–Dependent Coagulation Factor Complex Sales by Region (2020-2025) & (K Units)

Table 40. Asia Pacific Vitamin K–Dependent Coagulation Factor Complex Sales by Region (2026-2031) & (K Units)

Table 41. Asia Pacific Vitamin K–Dependent Coagulation Factor Complex Revenue by Region (2020-2025) & (US$ Million)

Table 42. Asia Pacific Vitamin K–Dependent Coagulation Factor Complex Revenue by Region (2026-2031) & (US$ Million)

Table 43. Latin America Vitamin K–Dependent Coagulation Factor Complex Revenue by Country: 2020 VS 2024 VS 2031 (US$ Million)

Table 44. Latin America Vitamin K–Dependent Coagulation Factor Complex Sales by Country (2020-2025) & (K Units)

Table 45. Latin America Vitamin K–Dependent Coagulation Factor Complex Sales by Country (2026-2031) & (K Units)

Table 46. Latin America Vitamin K–Dependent Coagulation Factor Complex Revenue by Country (2020-2025) & (US$ Million)

Table 47. Latin America Vitamin K–Dependent Coagulation Factor Complex Revenue by Country (2026-2031) & (US$ Million)

Table 48. Middle East and Africa Vitamin K–Dependent Coagulation Factor Complex Revenue by Country: 2020 VS 2024 VS 2031 (US$ Million)

Table 49. Middle East and Africa Vitamin K–Dependent Coagulation Factor Complex Sales by Country (2020-2025) & (K Units)

Table 50. Middle East and Africa Vitamin K–Dependent Coagulation Factor Complex Sales by Country (2026-2031) & (K Units)

Table 51. Middle East and Africa Vitamin K–Dependent Coagulation Factor Complex Revenue by Country (2020-2025) & (US$ Million)

Table 52. Middle East and Africa Vitamin K–Dependent Coagulation Factor Complex Revenue by Country (2026-2031) & (US$ Million)

Table 53. Global Vitamin K–Dependent Coagulation Factor Complex Sales (K Units) by Type (2020-2025)

Table 54. Global Vitamin K–Dependent Coagulation Factor Complex Sales (K Units) by Type (2026-2031)

Table 55. Global Vitamin K–Dependent Coagulation Factor Complex Sales Market Share by Type (2020-2025)

Table 56. Global Vitamin K–Dependent Coagulation Factor Complex Sales Market Share by Type (2026-2031)

Table 57. Global Vitamin K–Dependent Coagulation Factor Complex Revenue (US$ Million) by Type (2020-2025)

Table 58. Global Vitamin K–Dependent Coagulation Factor Complex Revenue (US$ Million) by Type (2026-2031)

Table 59. Global Vitamin K–Dependent Coagulation Factor Complex Revenue Market Share by Type (2020-2025)

Table 60. Global Vitamin K–Dependent Coagulation Factor Complex Revenue Market Share by Type (2026-2031)

Table 61. Global Vitamin K–Dependent Coagulation Factor Complex Price (US$/Unit) by Type (2020-2025)

Table 62. Global Vitamin K–Dependent Coagulation Factor Complex Price (US$/Unit) by Type (2026-2031)

Table 63. Global Vitamin K–Dependent Coagulation Factor Complex Sales (K Units) by Application (2020-2025)

Table 64. Global Vitamin K–Dependent Coagulation Factor Complex Sales (K Units) by Application (2026-2031)

Table 65. Global Vitamin K–Dependent Coagulation Factor Complex Sales Market Share by Application (2020-2025)

Table 66. Global Vitamin K–Dependent Coagulation Factor Complex Sales Market Share by Application (2026-2031)

Table 67. Global Vitamin K–Dependent Coagulation Factor Complex Revenue (US$ Million) by Application (2020-2025)

Table 68. Global Vitamin K–Dependent Coagulation Factor Complex Revenue (US$ Million) by Application (2026-2031)

Table 69. Global Vitamin K–Dependent Coagulation Factor Complex Revenue Market Share by Application (2020-2025)

Table 70. Global Vitamin K–Dependent Coagulation Factor Complex Revenue Market Share by Application (2026-2031)

Table 71. Global Vitamin K–Dependent Coagulation Factor Complex Price (US$/Unit) by Application (2020-2025)

Table 72. Global Vitamin K–Dependent Coagulation Factor Complex Price (US$/Unit) by Application (2026-2031)

Table 73. CSL Behring Company Information

Table 74. CSL Behring Description and Business Overview

Table 75. CSL Behring Vitamin K–Dependent Coagulation Factor Complex Sales (K Units), Revenue (US$ Million), Price (US$/Unit) and Gross Margin (2020-2025)

Table 76. CSL Behring Vitamin K–Dependent Coagulation Factor Complex Product

Table 77. CSL Behring Recent Developments/Updates

Table 78. Grifols Company Information

Table 79. Grifols Description and Business Overview

Table 80. Grifols Vitamin K–Dependent Coagulation Factor Complex Sales (K Units), Revenue (US$ Million), Price (US$/Unit) and Gross Margin (2020-2025)

Table 81. Grifols Vitamin K–Dependent Coagulation Factor Complex Product

Table 82. Grifols Recent Developments/Updates

Table 83. Octapharma Company Information

Table 84. Octapharma Description and Business Overview

Table 85. Octapharma Vitamin K–Dependent Coagulation Factor Complex Sales (K Units), Revenue (US$ Million), Price (US$/Unit) and Gross Margin (2020-2025)

Table 86. Octapharma Vitamin K–Dependent Coagulation Factor Complex Product

Table 87. Octapharma Recent Developments/Updates

Table 88. Prothya Biosolutions Company Information

Table 89. Prothya Biosolutions Description and Business Overview

Table 90. Prothya Biosolutions Vitamin K–Dependent Coagulation Factor Complex Sales (K Units), Revenue (US$ Million), Price (US$/Unit) and Gross Margin (2020-2025)

Table 91. Prothya Biosolutions Vitamin K–Dependent Coagulation Factor Complex Product

Table 92. Prothya Biosolutions Recent Developments/Updates

Table 93. Takeda Company Information

Table 94. Takeda Description and Business Overview

Table 95. Takeda Vitamin K–Dependent Coagulation Factor Complex Sales (K Units), Revenue (US$ Million), Price (US$/Unit) and Gross Margin (2020-2025)

Table 96. Takeda Vitamin K–Dependent Coagulation Factor Complex Product

Table 97. Takeda Recent Developments/Updates

Table 98. Biotest Company Information

Table 99. Biotest Description and Business Overview

Table 100. Biotest Vitamin K–Dependent Coagulation Factor Complex Sales (K Units), Revenue (US$ Million), Price (US$/Unit) and Gross Margin (2020-2025)

Table 101. Biotest Vitamin K–Dependent Coagulation Factor Complex Product

Table 102. Biotest Recent Developments/Updates

Table 103. Hualan Biological Company Information

Table 104. Hualan Biological Description and Business Overview

Table 105. Hualan Biological Vitamin K–Dependent Coagulation Factor Complex Sales (K Units), Revenue (US$ Million), Price (US$/Unit) and Gross Margin (2020-2025)

Table 106. Hualan Biological Vitamin K–Dependent Coagulation Factor Complex Product

Table 107. Hualan Biological Recent Developments/Updates

Table 108. Key Raw Materials Lists

Table 109. Raw Materials Key Suppliers Lists

Table 110. Vitamin K–Dependent Coagulation Factor Complex Distributors List

Table 111. Vitamin K–Dependent Coagulation Factor Complex Customers List

Table 112. Vitamin K–Dependent Coagulation Factor Complex Market Trends

Table 113. Vitamin K–Dependent Coagulation Factor Complex Market Drivers

Table 114. Vitamin K–Dependent Coagulation Factor Complex Market Challenges

Table 115. Vitamin K–Dependent Coagulation Factor Complex Market Restraints

Table 116. Research Programs/Design for This Report

Table 117. Key Data Information from Secondary Sources

Table 118. Key Data Information from Primary Sources

Table 119. Authors List of This Report

List of Figures

Figure 1. Product Picture of Vitamin K–Dependent Coagulation Factor Complex

Figure 2. Global Vitamin K–Dependent Coagulation Factor Complex Market Value Comparison by Type (2020-2031) & (US$ Million)

Figure 3. Global Vitamin K–Dependent Coagulation Factor Complex Market Share by Type: 2024 & 2031

Figure 4. Beriplex Product Picture

Figure 5. Profilnine Product Picture

Figure 6. Octaplex Product Picture

Figure 7. Prothromplex Product Picture

Figure 8. Cofact Product Picture

Figure 9. Other Product Picture

Figure 10. Global Vitamin K–Dependent Coagulation Factor Complex Market Value by Product Type, (US$ Million) & (2020-2031)

Figure 11. Global Vitamin K–Dependent Coagulation Factor Complex Market Share by Product Type: 2024 VS 2031

Figure 12. 3-Factor PCC Product Picture

Figure 13. 4-Factor PCC Product Picture

Figure 14. Recombinant Coagulation Complex Product Picture

Figure 15. Other Product Picture

Figure 16. Global Vitamin K–Dependent Coagulation Factor Complex Market Value by Source, (US$ Million) & (2020-2031)

Figure 17. Global Vitamin K–Dependent Coagulation Factor Complex Market Share by Source: 2024 VS 2031

Figure 18. Plasma-Derived Product Picture

Figure 19. Recombinant Bioengineered Product Picture

Figure 20. Global Vitamin K–Dependent Coagulation Factor Complex Market Value by Dosage Form, (US$ Million) & (2020-2031)

Figure 21. Global Vitamin K–Dependent Coagulation Factor Complex Market Share by Dosage Form: 2024 VS 2031

Figure 22. Lyophilized Powder for Injection Product Picture

Figure 23. Liquid Formulation Product Picture

Figure 24. Global Vitamin K–Dependent Coagulation Factor Complex Market Value by Application (2020-2031) & (US$ Million)

Figure 25. Global Vitamin K–Dependent Coagulation Factor Complex Market Share by Application: 2024 & 2031

Figure 26. Hemophilia B

Figure 27. Acquired Coagulation Factor Deficiency

Figure 28. Global Vitamin K–Dependent Coagulation Factor Complex Revenue, (US$ Million), 2020 VS 2024 VS 2031

Figure 29. Global Vitamin K–Dependent Coagulation Factor Complex Market Size (2020-2031) & (US$ Million)

Figure 30. Global Vitamin K–Dependent Coagulation Factor Complex Sales (2020-2031) & (K Units)

Figure 31. Global Vitamin K–Dependent Coagulation Factor Complex Average Price (US$/Unit) & (2020-2031)

Figure 32. Vitamin K–Dependent Coagulation Factor Complex Report Years Considered

Figure 33. Vitamin K–Dependent Coagulation Factor Complex Sales Share by Manufacturers in 2024

Figure 34. Global Vitamin K–Dependent Coagulation Factor Complex Revenue Share by Manufacturers in 2024

Figure 35. Global 5 and 10 Largest Vitamin K–Dependent Coagulation Factor Complex Players: Market Share by Revenue in Vitamin K–Dependent Coagulation Factor Complex in 2024

Figure 36. Vitamin K–Dependent Coagulation Factor Complex Market Share by Company Type (Tier 1, Tier 2, and Tier 3): 2020 VS 2024

Figure 37. Global Vitamin K–Dependent Coagulation Factor Complex Market Size by Region (US$ Million): 2020 VS 2024 VS 2031

Figure 38. North America Vitamin K–Dependent Coagulation Factor Complex Sales Market Share by Country (2020-2031)

Figure 39. North America Vitamin K–Dependent Coagulation Factor Complex Revenue Market Share by Country (2020-2031)

Figure 40. United States Vitamin K–Dependent Coagulation Factor Complex Revenue Growth Rate (2020-2031) & (US$ Million)

Figure 41. Canada Vitamin K–Dependent Coagulation Factor Complex Revenue Growth Rate (2020-2031) & (US$ Million)

Figure 42. Europe Vitamin K–Dependent Coagulation Factor Complex Sales Market Share by Country (2020-2031)

Figure 43. Europe Vitamin K–Dependent Coagulation Factor Complex Revenue Market Share by Country (2020-2031)

Figure 44. Germany Vitamin K–Dependent Coagulation Factor Complex Revenue Growth Rate (2020-2031) & (US$ Million)

Figure 45. France Vitamin K–Dependent Coagulation Factor Complex Revenue Growth Rate (2020-2031) & (US$ Million)

Figure 46. U.K. Vitamin K–Dependent Coagulation Factor Complex Revenue Growth Rate (2020-2031) & (US$ Million)

Figure 47. Italy Vitamin K–Dependent Coagulation Factor Complex Revenue Growth Rate (2020-2031) & (US$ Million)

Figure 48. Russia Vitamin K–Dependent Coagulation Factor Complex Revenue Growth Rate (2020-2031) & (US$ Million)

Figure 49. Asia Pacific Vitamin K–Dependent Coagulation Factor Complex Sales Market Share by Region (2020-2031)

Figure 50. Asia Pacific Vitamin K–Dependent Coagulation Factor Complex Revenue Market Share by Region (2020-2031)

Figure 51. China Vitamin K–Dependent Coagulation Factor Complex Revenue Growth Rate (2020-2031) & (US$ Million)

Figure 52. Japan Vitamin K–Dependent Coagulation Factor Complex Revenue Growth Rate (2020-2031) & (US$ Million)

Figure 53. South Korea Vitamin K–Dependent Coagulation Factor Complex Revenue Growth Rate (2020-2031) & (US$ Million)

Figure 54. India Vitamin K–Dependent Coagulation Factor Complex Revenue Growth Rate (2020-2031) & (US$ Million)

Figure 55. Australia Vitamin K–Dependent Coagulation Factor Complex Revenue Growth Rate (2020-2031) & (US$ Million)

Figure 56. China Taiwan Vitamin K–Dependent Coagulation Factor Complex Revenue Growth Rate (2020-2031) & (US$ Million)

Figure 57. Southeast Asia Vitamin K–Dependent Coagulation Factor Complex Revenue Growth Rate (2020-2031) & (US$ Million)

Figure 58. Latin America Vitamin K–Dependent Coagulation Factor Complex Sales Market Share by Country (2020-2031)

Figure 59. Latin America Vitamin K–Dependent Coagulation Factor Complex Revenue Market Share by Country (2020-2031)

Figure 60. Mexico Vitamin K–Dependent Coagulation Factor Complex Revenue Growth Rate (2020-2031) & (US$ Million)

Figure 61. Brazil Vitamin K–Dependent Coagulation Factor Complex Revenue Growth Rate (2020-2031) & (US$ Million)

Figure 62. Argentina Vitamin K–Dependent Coagulation Factor Complex Revenue Growth Rate (2020-2031) & (US$ Million)

Figure 63. Middle East and Africa Vitamin K–Dependent Coagulation Factor Complex Sales Market Share by Country (2020-2031)

Figure 64. Middle East and Africa Vitamin K–Dependent Coagulation Factor Complex Revenue Market Share by Country (2020-2031)

Figure 65. Turkey Vitamin K–Dependent Coagulation Factor Complex Revenue Growth Rate (2020-2031) & (US$ Million)

Figure 66. Saudi Arabia Vitamin K–Dependent Coagulation Factor Complex Revenue Growth Rate (2020-2031) & (US$ Million)

Figure 67. UAE Vitamin K–Dependent Coagulation Factor Complex Revenue Growth Rate (2020-2031) & (US$ Million)

Figure 68. Global Sales Market Share of Vitamin K–Dependent Coagulation Factor Complex by Type (2020-2031)

Figure 69. Global Revenue Market Share of Vitamin K–Dependent Coagulation Factor Complex by Type (2020-2031)

Figure 70. Global Vitamin K–Dependent Coagulation Factor Complex Price (US$/Unit) by Type (2020-2031)

Figure 71. Global Sales Market Share of Vitamin K–Dependent Coagulation Factor Complex by Application (2020-2031)

Figure 72. Global Revenue Market Share of Vitamin K–Dependent Coagulation Factor Complex by Application (2020-2031)

Figure 73. Global Vitamin K–Dependent Coagulation Factor Complex Price (US$/Unit) by Application (2020-2031)

Figure 74. Vitamin K–Dependent Coagulation Factor Complex Value Chain

Figure 75. Channels of Distribution (Direct Vs Distribution)

Figure 76. Bottom-up and Top-down Approaches for This Report

Figure 77. Data Triangulation

Figure 78. Key Executives Interviewed

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